Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | ACP1 | P24666 | 3/20 | 0.36 |
| ▸ | CDC25B | P30305 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064162 | 0.81 | SIRT2 (0.44) | KMT2AMEN1MAPTPTPN1ACP1 | |
| SCHEMBL17064159 | 0.78 | SMN1; SMN2 (0.36) | MMP2MMP9KMT2AMEN1MAPT | |
| SCHEMBL17064143 | 0.78 | NPC1 (0.38) | KMT2AMEN1MAPTPOLBRECQL | |
| SCHEMBL17064154 | 0.77 | MMP2 (0.38) | MMP2MMP9KMT2AMAPTPTPN1 | |
| SCHEMBL21428296 | 0.74 | KMT2A (0.41) | KMT2AMEN1MAPTPTPN1ACP1 | |
| SCHEMBL17064155 | 0.71 | SMN1; SMN2 (0.50) | KMT2AMEN1PTPN1ACP1CDC25B | |
| SCHEMBL17064149 | 0.71 | SMN1; SMN2 (0.46) | KMT2AKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL17064140 | 0.70 | SMN1; SMN2 (0.49) | KDM4ENPSR1TDP1ALDH1A1HPGD | |
| SCHEMBL11005871 | 0.68 | ALDH1A1 (0.39) | MMP2MMP9KMT2AMEN1MAPT | |
| SCHEMBL11005383 | 0.68 | ALDH1A1 (0.39) | MMP2MMP9KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3114117-B1 | IODINE(III)-MEDIATED RADIOFLUORINATION | MASSACHUSETTS GEN HOSPITAL (US) | 2019-10-02 | — | — | EP | disclosed |
| US-9957231-B2 | Iodine(II)-mediated radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160362375-A1 | Iodine(III)-Mediated Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2016-12-15 | — | — | US | disclosed |
| US-9434699-B2 | Iodine(III)-mediated radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2016-09-06 | — | — | US | disclosed |
| US-20150252007-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252007-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | TPO, FLI1, SSTR3 | MMP2 3018/4885MMP9 4059/4885KMT2A 1626/4885 |
| US-20160362375-A1 | Iodine(III)-Mediated Radiofluorination | TPO, FLI1, SSTR3 | MMP2 3018/4885MMP9 4059/4885KMT2A 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.