Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064143 | 0.83 | NPC1 (0.38) | SMN1; SMN2MAPTNPC1RAB9ATDP2 | |
| SCHEMBL17064155 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDPTPN1CDC25BNPC1 | |
| SCHEMBL17064149 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDNPC1RAB9ATDP2 | |
| SCHEMBL17064159 | 0.77 | SMN1; SMN2 (0.36) | MMP2MMP9SMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL17064150 | 0.77 | MMP2 (0.44) | MMP2MMP9MMP3L3MBTL1HPGD | |
| SCHEMBL17064140 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDNPC1RAB9APTGS2 | |
| SCHEMBL2710911 | 0.76 | PTPN1 (0.40) | PTPN1CDC25BHSD11B1 | |
| SCHEMBL3966742 | 0.74 | ELANE (0.42) | MMP2MMP9L3MBTL1HSD11B1 | |
| SCHEMBL24029558 | 0.67 | ALDH1A1 (0.60) | MMP3SMN1; SMN2MAPTAPPALDH1A1 | |
| SCHEMBL45621 | 0.67 | ALDH1A1 (0.60) | MMP3SMN1; SMN2MAPTAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3114117-B1 | IODINE(III)-MEDIATED RADIOFLUORINATION | MASSACHUSETTS GEN HOSPITAL (US) | 2019-10-02 | — | — | EP | disclosed |
| US-9957231-B2 | Iodine(II)-mediated radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160362375-A1 | Iodine(III)-Mediated Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2016-12-15 | — | — | US | disclosed |
| US-9434699-B2 | Iodine(III)-mediated radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2016-09-06 | — | — | US | disclosed |
| US-20150252007-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252007-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | TPO, FLI1, SSTR3 | MMP2 3018/4885MMP9 4059/4885MMP3 2003/4885 |
| US-20160362375-A1 | Iodine(III)-Mediated Radiofluorination | TPO, FLI1, SSTR3 | MMP2 3018/4885MMP9 4059/4885MMP3 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.