Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064211 | 0.83 | LMNA (0.45) | KMT2A | |
| SCHEMBL17073927 | 0.82 | MEN1 (0.44) | KDRNPC1RAB9AHPGDKMT2A | |
| SCHEMBL17064212 | 0.77 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2 | |
| SCHEMBL17064204 | 0.77 | RXFP1 (0.40) | KMT2AMEN1SMN1; SMN2TDP1POLB | |
| SCHEMBL17064215 | 0.77 | SMN1; SMN2 (0.43) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL18643507 | 0.74 | RAB9A (0.42) | KDRNPC1RAB9ACYP1A2HPGD | |
| SCHEMBL17073930 | 0.74 | RPS6KA3 (0.47) | NPC1RAB9ACYP1A2HPGDCYP2C19 | |
| SCHEMBL17064201 | 0.73 | KCNK3 (0.44) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30369780 | 0.72 | CYP1A2 (0.59) | CYP1A2HPGDCYP2C19KMT2AMEN1 | |
| SCHEMBL29571859 | 0.70 | ALDH1A1 (0.45) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113618-B1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2018-07-04 | — | — | EP | disclosed |
| US-9920017-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-20 | — | — | US | disclosed |
| US-9920017-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-20 | — | — | US | disclosed |
| US-9920017-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-20 | — | — | US | disclosed |
| US-20170073318-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
| US-20170073318-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
| US-20170073318-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-03-16 | — | — | US | disclosed |
| EP-3113618-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015132313-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2015-09-11 | — | — | WO | disclosed |
| WO-2015132313-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2015-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073318-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | KDR 4800/4885NPC1 3008/4885RAB9A 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.