SCHEMBL1706539

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1706540	0.85	HTR1A (0.41)	HTR1ADCTPP1HRH4DRD2DRD3
	SCHEMBL1706908	0.83	PLOD2 (0.40)	DCTPP1HRH4DRD2PLOD2PLOD3
	SCHEMBL1706915	0.83	ADRA2C (0.40)	DCTPP1HRH4DRD2PLOD2PLOD3
	SCHEMBL1705599	0.77	NPC1 (0.41)	DCTPP1HRH4DRD2PLOD2PLOD3
	SCHEMBL1705567	0.73	SMN1; SMN2 (0.40)	HTR1AHRH4DRD3HTR2AHTR7
	SCHEMBL1705603	0.73	SMN1; SMN2 (0.40)	HTR1AHRH4DRD3HTR2AHTR7
	SCHEMBL1706085	0.73	SMN1; SMN2 (0.40)	HTR1AHRH4DRD3HTR2AHTR7
	SCHEMBL1706513	0.72	F10 (0.43)	DCTPP1PLOD2PLOD3PLOD1NPC1
	SCHEMBL12156290	0.71	GUSB (0.38)	HTR1AHRH4DRD3HTR2AHTR7
	SCHEMBL3103456	0.71	F10 (0.40)	DCTPP1PLOD2PLOD3PLOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.