Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | DCLK1 | O15075 | 5/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 4/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706539 | 0.85 | HTR1A (0.40) | HTR1ADCLK1LRRK2MAPK7DCTPP1 | |
| SCHEMBL1705585 | 0.83 | ADRA2C (0.41) | DCTPP1HTR6DRD2HRH4NPC1 | |
| SCHEMBL1706545 | 0.83 | HRH4 (0.41) | DCTPP1HTR6DRD2HRH4NPC1 | |
| SCHEMBL1756052 | 0.75 | PLOD2 (0.43) | HTR1ADCTPP1BRD4HTR6DRD2 | |
| SCHEMBL1706531 | 0.74 | MEN1 (0.41) | DCTPP1HTR6DRD2DRD3HRH4 | |
| SCHEMBL12156021 | 0.74 | CCNC (0.40) | DCTPP1HTR6DRD2HRH4NPC1 | |
| SCHEMBL12156234 | 0.73 | SMN1; SMN2 (0.40) | HTR1ABRD4HTR6DRD3HTR2A | |
| SCHEMBL10080284 | 0.70 | RAD52 (0.41) | HTR1ABRD4HTR6DRD3HTR2A | |
| SCHEMBL1706908 | 0.70 | PLOD2 (0.40) | DCTPP1DRD2HRH4NPC1 | |
| SCHEMBL1706915 | 0.70 | ADRA2C (0.40) | DCTPP1DRD2HRH4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177512-B1 | INHIBITOR OF BINDING OF S1P1 | TAISHO PHARMACEUTICAL CO LTD (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-8048898-B2 | Inhibitor of binding of S1P1 | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-11-01 | — | — | US | disclosed |
| US-8048898-B2 | Inhibitor of binding of S1P1 | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-11-01 | — | — | US | disclosed |
| US-8048898-B2 | Inhibitor of binding of S1P1 | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20100234594-A1 | INHIBITOR OF BINDING OF S1P1 | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234594-A1 | INHIBITOR OF BINDING OF S1P1 | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234594-A1 | INHIBITOR OF BINDING OF S1P1 | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2177512-A1 | INHIBITOR OF BINDING OF S1P1 | Taisho Pharmaceutical Co. Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234594-A1 | INHIBITOR OF BINDING OF S1P1 | S1PR1, S1PR3, EDNRB | HTR1A 437/4885DCLK1 1059/4885LRRK2 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.