⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108066 | 0.85 | OR51E2 (0.33) | — | |
| SCHEMBL8638776 | 0.76 | LDHA (0.35) | — | |
| SCHEMBL195623 | 0.74 | — | — | |
| SCHEMBL6773592 | 0.73 | — | — | |
| SCHEMBL9912442 | 0.73 | — | — | |
| SCHEMBL7396316 | 0.72 | ECE1 (0.41) | — | |
| SCHEMBL2113139 | 0.71 | — | — | |
| SCHEMBL29039515 | 0.71 | ALDH1A1 (0.43) | — | |
| SCHEMBL2373214 | 0.69 | — | — | |
| SCHEMBL31107449 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530637-B | Preparation method of single-functionalized branched polyethylene glycol | 厦门赛诺邦格生物科技股份有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-112023122-A | In-situ injection jelly as well as preparation method and application thereof | 北京爱特康医疗科技有限公司 | 2020-12-04 | — | — | CN | claimed |
| US-20070135349-A1 | Method for increasing the serum half-life of a biologically active molecule | DRUMMOND ROBERT J | 2007-06-14 | — | — | US | claimed |
| US-20070060513-A9 | Method for increasing the serum half-life of a biologically active molecule | DRUMMOND ROBERT J | 2007-03-15 | — | — | US | claimed |
| US-20050197297-A1 | Method for increasing the serum half-life of a biologically active molecule | DRUMMOND ROBERT J (US) | 2005-09-08 | — | — | US | claimed |
| EP-1062230-B1 | METHOD FOR INCREASING THE SERUM HALF-LIFE OF A BIOLOGICALLY ACTIVE MOLECULE | CHIRON CORP (US) | 2004-10-13 | — | — | EP | claimed |
| US-20020182705-A1 | Method for increasing the serum half-life of a biologically active molecule | CHIRON CORPORATION | 2002-12-05 | — | — | US | claimed |
| US-6423685-B1 | CONJUGATING POLYMER (POLYETHYLENE GLYCOL) TO BIOLOGICALLY ACTIVE MOLECULE (POLYPEPTIDE); HUMAN UROKINASE PLASMINOGEN ACTIVATOR | CHIRON CORPORATION | 2002-07-23 | — | — | US | claimed |
| US-20020086819-A1 | METHOD FOR INCREASING THE SERUM HALF-LIFE OF A BIOLOGICALLY ACTIVE MOLECULE | CHIRON CORPORATION | 2002-07-04 | — | — | US | claimed |
| EP-1062230-A1 | METHOD FOR INCREASING THE SERUM HALF-LIFE OF A BIOLOGICALLY ACTIVE MOLECULE | Chiron Corporation (US) | 2000-12-27 | — | — | EP | claimed |
| WO-1999045026-A1 | METHOD FOR INCREASING THE SERUM HALF-LIFE OF A BIOLOGICALLY ACTIVE MOLECULE | CHIRON CORPORATION (US) | 1999-09-10 | — | — | WO | claimed |
| US-5547981-A | Taxol-7-carbazates | ENZON, INC. (US) | 1996-08-20 | — | — | US | claimed |
| CN-117487043-A | Aldehyde hyaluronic acid derivative and preparation method thereof | 中国科学院长春应用化学研究所 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023114418-A1 | IMPLANTABLE SCAFFOLDS FOR IMMUNOTHERAPEUTIC AND OTHER USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-22 | — | — | WO | disclosed |
| CN-108530636-B | Single functionalized branched polyethylene glycol | 厦门赛诺邦格生物科技股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-108530637-B | Preparation method of single-functionalized branched polyethylene glycol | 厦门赛诺邦格生物科技股份有限公司 | 2021-03-30 | — | — | CN | disclosed |
| WO-2001043774-A1 | METHODS OF TREATING CENTRAL NERVOUS SYSTEM ISCHEMIC OR HEMORRHAGIC INJURY USING ANTI ALPHA4 INTEGRIN ANTAGONISTS | BIOGEN, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| WO-2000064474-A1 | METHOD FOR THE TREATMENT OF FIBROSIS USING AN ANTAGONIST OF THE INTEGRIN ALPHA-4 SUBUNIT | BIOGEN, INC. (US) | 2000-11-02 | — | — | WO | disclosed |
| WO-2000023114-A2 | POLYMER CONJUGATES OF INTERFERON BETA- 1A AND THEIR USES | BIOGEN, INC. (US) | 2000-04-27 | — | — | WO | disclosed |
| US-5547981-A | Taxol-7-carbazates | ENZON, INC. (US) | 1996-08-20 | — | — | US | disclosed |