Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KDM5C | P41229 | 2/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29162925 | 0.79 | ALDH1A1 (0.32) | LDHASRREGLN1KDM4EKDM5C | |
| SCHEMBL28799538 | 0.79 | FFAR3 (0.43) | LDHASRREGLN1KDM4EKDM5C | |
| SCHEMBL30441811 | 0.79 | TSHR (0.43) | LDHASRREGLN1KDM4EKDM5C | |
| SCHEMBL170662 | 0.76 | — | — | |
| SCHEMBL3981769 | 0.75 | HDAC3 (0.46) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL8352247 | 0.75 | LDHA (0.50) | LDHASRREGLN1KDM4EKDM5C | |
| SCHEMBL7108066 | 0.75 | OR51E2 (0.33) | LDHASRROR51E2 | |
| SCHEMBL3051875 | 0.74 | — | — | |
| SCHEMBL7396316 | 0.74 | ECE1 (0.41) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL21635548 | 0.74 | GRIK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807983-A | HUMAN GONADOTROPIN RELEASING HORMONE | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-09-15 | — | — | US | disclosed |