Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021950 | 0.85 | MAPK1 (0.52) | ALDH1A1CYP3A4ALOX15L3MBTL1MAPK1 | |
| SCHEMBL11809474 | 0.84 | L3MBTL1 (0.59) | ALDH1A1CYP3A4ALOX15L3MBTL1MAPK1 | |
| SCHEMBL29665784 | 0.84 | MAPT (0.52) | ALDH1A1CYP3A4ALOX15L3MBTL1GPR35 | |
| SCHEMBL199359 | 0.84 | MAPT (0.52) | ALDH1A1CYP3A4ALOX15L3MBTL1GPR35 | |
| SCHEMBL6505797 | 0.82 | MAPT (0.50) | ALDH1A1CYP3A4ALOX15L3MBTL1GPR35 | |
| SCHEMBL2413345 | 0.82 | TDP1 (0.50) | ALDH1A1ALOX15MAPK1HSD17B10CA12 | |
| SCHEMBL14247146 | 0.82 | MAPT (0.50) | ALDH1A1CYP3A4ALOX15L3MBTL1TDP1 | |
| SCHEMBL30110723 | 0.79 | TDP1 (0.52) | ALDH1A1CYP3A4ALOX15L3MBTL1GPR35 | |
| SCHEMBL564506 | 0.79 | TDP1 (0.52) | ALDH1A1CYP3A4ALOX15L3MBTL1GPR35 | |
| SCHEMBL810816 | 0.78 | TDP1 (0.50) | ALDH1A1CYP3A4ALOX15MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837732-A1 | NOVEL CATALYTIC MATERIALS | University of Tartu (EE) | 2021-06-23 | — | — | EP | disclosed |
| EP-2041119-B1 | PYRAZOLYLBENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND USE THEREOF | AVENTIS PHARMA SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| US-9126969-B2 | Pyrazolylbenzimidazole derivatives, compositions containing them and use thereof | AVENTIS PHARMA S.A. (FR) | 2015-09-08 | — | — | US | disclosed |