Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PCTP | Q9UKL6 | 10/20 | 0.56 |
| ▸ | STARD10 | Q9Y365 | 3/20 | 0.56 |
| ▸ | STARD7 | Q9NQZ5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358245 | 0.84 | ALDH1A1 (0.80) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 | |
| SCHEMBL12903628 | 0.84 | PCTP (0.77) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 | |
| SCHEMBL17066575 | 0.79 | PCTP (0.77) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 | |
| SCHEMBL17284883 | 0.78 | PCTP (0.66) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 | |
| SCHEMBL12903623 | 0.76 | PCTP (0.80) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 | |
| SCHEMBL17066524 | 0.75 | PCTP (0.79) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 | |
| SCHEMBL17066525 | 0.74 | PCTP (0.78) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 | |
| SCHEMBL1234607 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 | |
| SCHEMBL17066522 | 0.73 | PCTP (0.80) | ALDH1A1PCTPSTARD10STARD7LMNA | |
| SCHEMBL17066528 | 0.72 | PCTP (0.78) | SMN1; SMN2ALDH1A1PCTPSTARD10STARD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9126938-B2 | Phosphatidylcholine transfer protein inhibitors | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-09-08 | — | — | US | disclosed |