Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730719 | 0.77 | ALK (0.33) | CTSK | |
| SCHEMBL15724396 | 0.73 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL25979376 | 0.73 | HTT (0.36) | CYP19A1 | |
| SCHEMBL22275817 | 0.72 | L3MBTL1 (0.40) | — | |
| SCHEMBL17066973 | 0.72 | NPC1 (0.44) | — | |
| SCHEMBL25109584 | 0.72 | HTT (0.32) | — | |
| SCHEMBL22275391 | 0.69 | KDM5A (0.33) | CTSK | |
| SCHEMBL22275561 | 0.66 | — | — | |
| SCHEMBL28309161 | 0.66 | JAK3 (0.41) | — | |
| Cyanide SCHEMBL27780621 | 0.65 | DRD2 (0.36) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729448-B1 | COMPOUNDS FOR THE TREATMENT OF HIV | GILEAD SCIENCES INC (US) | 2015-09-09 | — | — | EP | disclosed |