Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 8/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26419133 | 0.81 | ADORA2A (0.37) | JAK3JAK2JAK1PARP1 | |
| SCHEMBL26420237 | 0.81 | AR (0.36) | JAK2JAK1PARP1 | |
| SCHEMBL30621006 | 0.80 | TGFBR1 (0.36) | JAK2JAK1PARP1 | |
| SCHEMBL952140 | 0.76 | L3MBTL1 (0.50) | JAK3L3MBTL1KDM4EALDH1A1NPC1 | |
| SCHEMBL12486040 | 0.75 | L3MBTL1 (0.43) | JAK3L3MBTL1KDM4EALDH1A1NPC1 | |
| SCHEMBL22275817 | 0.74 | L3MBTL1 (0.40) | L3MBTL1KDM4EALDH1A1NPC1HTT | |
| SCHEMBL19780673 | 0.73 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL25979376 | 0.72 | HTT (0.36) | L3MBTL1KDM4EALDH1A1NPC1HTT | |
| SCHEMBL17067013 | 0.71 | L3MBTL1 (0.40) | L3MBTL1KDM4EALDH1A1NPC1HTT | |
| SCHEMBL26133925 | 0.71 | L3MBTL1 (0.40) | JAK3L3MBTL1KDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110022875-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2019-07-16 | — | — | CN | claimed |
| CN-110022875-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2019-07-16 | — | — | CN | disclosed |