Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275817 | 0.78 | L3MBTL1 (0.40) | HTTSMN1; SMN2L3MBTL1COMTKDM4E | |
| SCHEMBL25109584 | 0.78 | HTT (0.32) | HTTSMN1; SMN2L3MBTL1COMTKDM4E | |
| SCHEMBL17066973 | 0.78 | NPC1 (0.44) | HTTSMN1; SMN2L3MBTL1KDM4ELMNA | |
| SCHEMBL22275391 | 0.76 | KDM5A (0.33) | HTTSMN1; SMN2 | |
| SCHEMBL17066892 | 0.73 | PGR (0.32) | CYP19A1 | |
| SCHEMBL12179227 | 0.72 | — | — | |
| SCHEMBL12888201 | 0.72 | SMN1; SMN2 (0.43) | HTTSMN1; SMN2L3MBTL1COMTKDM4E | |
| SCHEMBL22275561 | 0.72 | — | — | |
| SCHEMBL28309161 | 0.72 | JAK3 (0.41) | HTTSMN1; SMN2L3MBTL1KDM4ELMNA | |
| SCHEMBL116289 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377474-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-08-16 | — | — | EP | disclosed |