Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17067708 | 0.71 | USP7 (0.39) | MAP4K4DHFRUSP7ALOX5APFEN1 | |
| SCHEMBL23931349 | 0.70 | DHFR (0.50) | CYP2A6DHFRPLA2G10LMNATERT | |
| SCHEMBL14934141 | 0.69 | GAA (0.46) | MAP4K4DHFRUSP7ALOX5APFEN1 | |
| SCHEMBL14934133 | 0.68 | USP7 (0.46) | MAP4K4DHFRUSP7ALOX5APFEN1 | |
| SCHEMBL23931363 | 0.68 | SCN2A (0.54) | CYP2A6PLA2G10LMNATERTFGFR1 | |
| SCHEMBL3647945 | 0.67 | MAP4K4 (0.62) | MAP4K4USP7 | |
| SCHEMBL14934137 | 0.67 | JAK2 (0.48) | MAP4K4DHFRUSP7CLK1CYP1A2 | |
| SCHEMBL14934135 | 0.66 | CYP11B2 (0.57) | MAP4K4USP7ALOX5APFEN1EPHB4 | |
| SCHEMBL14934142 | 0.66 | MKNK1 (0.45) | MAP4K4CYP1A2KCNH2MINK1TNIK | |
| SCHEMBL11338752 | 0.66 | CHEK2 (0.49) | MAP4K4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773631-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | EP | disclosed |
| WO-2013064519-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-10 | — | — | WO | disclosed |