Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16441216 | 0.87 | CNR2 (0.39) | CNR2TSHRL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL26758488 | 0.81 | TSHR (0.42) | SMN1; SMN2CNR2TSHRL3MBTL1MTNR1A | |
| SCHEMBL21907199 | 0.81 | MTNR1A (0.33) | CNR2TSHRL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL2742841 | 0.81 | TSHR (0.42) | SMN1; SMN2CNR2TSHRL3MBTL1MTNR1A | |
| SCHEMBL18090276 | 0.81 | MTNR1A (0.33) | CNR2TSHRL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL29263611 | 0.80 | MTNR1A (0.33) | CNR2TSHRL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL17766460 | 0.80 | MTNR1A (0.33) | CNR2TSHRL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL31296167 | 0.80 | MTNR1A (0.33) | CNR2TSHRL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL23135478 | 0.80 | TSHR (0.47) | SMN1; SMN2CNR2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL25680587 | 0.79 | FAAH (0.48) | SMN1; SMN2TSHRALDH1A1POLBNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2378288-B1 | Unnatural reactive amino acid genetic code additions | SCRIPPS RESEARCH INST (US) | 2015-09-09 | — | — | EP | disclosed |