Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | CDC25A | P30304 | 2/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | CDC25C | P30307 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,6-Dimethoxyquinone SCHEMBL570683 | 0.86 | HKDC1 (1.00) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| SCHEMBL684719 | 0.73 | MAPT (0.73) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| 2,6-Dimethoxyquinone SCHEMBL11304693 | 0.72 | HKDC1 (0.71) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| SCHEMBL7115894 | 0.71 | ALOX5 (1.00) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| SCHEMBL21729822 | 0.71 | HKDC1 (0.70) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| SCHEMBL9364524 | 0.71 | MAPT (0.70) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| SCHEMBL2404062 | 0.71 | HKDC1 (0.61) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| SCHEMBL197028 | 0.71 | HKDC1 (0.70) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| SCHEMBL8581167 | 0.70 | IDO1 (0.61) | KDM4EMAPTHKDC1CYP3A4MAPK1 | |
| Benzoquinone SCHEMBL5695835 | 0.69 | TDP1 (0.54) | KDM4EMAPTCYP3A4MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027279-B1 | Phenolic compounds with cosmetic and therapeutic applications | LIBRAGEN (FR) | 2012-04-18 | — | — | EP | disclosed |
| EP-2202237-A1 | Hydrosoluble [6)-O-alpha-d-glcp-(1->]n-6-o-bêta-d-glcp-(1->-phenllic derivatives with dermocosmetic, nutritional and therapeutic applications, and compositions containing said water soluble compounds | Libragen (FR) | 2010-06-30 | — | — | EP | disclosed |