SCHEMBL170688

SCHEMBL170688

C=C(C)C(=O)Oc1ccc(N(c2ccc(-c3ccc(OC(C)=O)cc3)cc2)c2ccc(C)c(CCCC)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.38
▸ HSD17B10 Q99714 2/20 0.36
▸ GFER P55789 1/20 0.35
▸ FPR1 P21462 1/20 0.35
▸ LMNA P02545 2/20 0.34
▸ GAA P10253 1/20 0.34
▸ ALOX5 P09917 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ ACHE P22303 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ HPGD P15428 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14402755 0.98 ELANE (0.37) ELANEHSD17B10GFERFPR1LMNA
SCHEMBL14402958 0.98 ELANE (0.37) ELANEHSD17B10GFERFPR1LMNA
SCHEMBL14402956 0.92 THRB (0.44) ELANEKMT2AATMHPGDTHRB
SCHEMBL14402819 0.92 THRB (0.44) ELANEKMT2AATMHPGDTHRB
SCHEMBL14402957 0.92 THRB (0.44) ELANEKMT2AATMHPGDTHRB
SCHEMBL14402960 0.87 THRB (0.35) ELANEKMT2AATMMAPTTDP1
SCHEMBL172562 0.84 THRB (0.50) HPGDTHRB
SCHEMBL13968315 0.84 THRB (0.50) HPGDTHRB
SCHEMBL27695940 0.83 ELANE (0.41) ELANEGAAALOX5KMT2AACHE
SCHEMBL172503 0.83 THRB (0.43) ELANEHPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
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