Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402961 | 0.94 | TSHR (0.36) | THRBATMKMT2ATSHRTHRA | |
| SCHEMBL172441 | 0.92 | THRB (0.47) | THRBTSHRTHRA | |
| SCHEMBL172503 | 0.92 | THRB (0.43) | THRBELANETSHRTHRA | |
| SCHEMBL14402958 | 0.89 | ELANE (0.37) | THRBELANEATMKMT2A | |
| SCHEMBL14402755 | 0.89 | ELANE (0.37) | THRBELANEATMKMT2A | |
| SCHEMBL14402565 | 0.87 | THRB (0.37) | THRBKMT2ATSHRTHRACYP3A4 | |
| SCHEMBL170688 | 0.87 | ELANE (0.38) | THRBELANEATMKMT2ATDP1 | |
| SCHEMBL14402819 | 0.83 | THRB (0.44) | THRBELANEATMKMT2ATSHR | |
| SCHEMBL14402956 | 0.83 | THRB (0.44) | THRBELANEATMKMT2ATSHR | |
| SCHEMBL14402957 | 0.83 | THRB (0.44) | THRBELANEATMKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847881-A2 | Image forming apparatus, image forming method, and process cartridge | Ricoh Company, Ltd. (JP) | 2007-10-24 | — | — | EP | disclosed |