SCHEMBL172503

SCHEMBL172503

C=CC(=O)OCc1ccc(N(c2ccc(OC(=O)C(=C)C)cc2)c2ccc(C)c(CCCC)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 4/20 0.43
▸ THRA P10827 2/20 0.34
▸ HPGD P15428 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ TGM2 P21980 1/20 0.31
▸ ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172441 0.94 THRB (0.47) THRBTHRAHPGDTSHRTGM2
SCHEMBL14402565 0.93 THRB (0.37) THRBTHRAHPGDTSHRTGM2
SCHEMBL170675 0.93 THRB (0.51) THRBTHRAHPGDTSHRTGM2
SCHEMBL14402960 0.92 THRB (0.35) THRBTHRATSHRELANE
SCHEMBL14402810 0.89 THRB (0.41) THRBTHRAHPGDTSHRTGM2
SCHEMBL14402957 0.89 THRB (0.44) THRBTHRAHPGDTSHRELANE
SCHEMBL14402956 0.89 THRB (0.44) THRBTHRAHPGDTSHRELANE
SCHEMBL14402819 0.89 THRB (0.44) THRBTHRAHPGDTSHRELANE
SCHEMBL14402961 0.85 TSHR (0.36) THRBTHRAHPGDTSHRTGM2
SCHEMBL14402958 0.84 ELANE (0.37) THRBELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 — — EP disclosed
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