SCHEMBL1706952

SCHEMBL1706952

C=CCOC(=O)[C@@H](N)C[SeH]

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
CYP3A4 P08684 1/20 0.37
TSHR P16473 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
GRIK1 P39086 2/20 0.33
GRIK2 Q13002 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SNCA P37840 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2286672 0.81 MAPT (0.40) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL2516533 0.81 MAPT (0.40) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL5341469 0.81 MAPT (0.40) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL3637092 0.79 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR
Hydrochloric Acid SCHEMBL6573325 0.79 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL8824184 0.79 TSHR (0.43) MAPTCACNA1BAPBA1CYP3A4TSHR
Hydrochloric Acid SCHEMBL2302945 0.79 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL3634048 0.79 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL2355766 0.79 PTGS1 (0.43) MAPTCACNA1BAPBA1CYP3A4TSHR
Hydrochloric Acid SCHEMBL2302935 0.79 MAPT (0.39) MAPTCACNA1BAPBA1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1968620-B1 Compositions comprising powdered garlic (Allium sativum linn.) and a concentrate of organic selenium compounds for nutritional supplementation MAJEED MUHAMMED (US) 2012-04-18 EP claimed
US-20060240126-A1 COMPOSITIONS CONTAINING ALLIUM SATIVUM LINN. (GARLIC) NATURALLY ENRICHED WITH ORGANIC SELENIUM COMPOUNDS FOR NUTRITIONAL SUPPLEMENTATION SAMI LABS LIMITED 2006-10-26 US claimed
WO-2005023274-A1 TREATMENT AND PREVENTION OF INFLAMMATORY DISEASE AND MITOCHONDRIAL DYSFUNCTION WITH HIGH DOSE SELENIUM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2005-03-17 WO claimed
US-20240115666-A1 COMPOSITIONS AND METHODS FOR REDUCING GAMMA-GLUTAMYLTRANSFERASE LEVELS LILE METHOD RESEARCH, LLC (US) 2024-04-11 US disclosed
US-20240108695-A1 COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING TUBERCULOSIS AND MRSA LILE METHOD RESEARCH, LLC (US) 2024-04-04 US disclosed
US-20240108682-A1 COMPOSITIONS AND METHODS FOR INCREASING GLUTATHIONE LEVELS LILE METHOD RESEARCH, LLC (US) 2024-04-04 US disclosed
US-20240108696-A1 COMPOSITIONS AND METHODS FOR IMPROVING VACCINE THERAPY LILE METHOD RESEARCH, LLC (US) 2024-04-04 US disclosed
WO-2024064264-A2 COMPOSITIONS AND METHODS FOR INCREASING GLUTATHIONE LEVELS LILE METHOD RESEARCH, LLC (US) 2024-03-28 WO disclosed
EP-1968620-B1 Compositions comprising powdered garlic (Allium sativum linn.) and a concentrate of organic selenium compounds for nutritional supplementation MAJEED MUHAMMED (US) 2012-04-18 EP disclosed
US-20070026090-A1 Treatment and prevention of inflammatory disease and mitochondrial dysfunction with high dose selenium YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2007-02-01 US disclosed
US-20060240126-A1 COMPOSITIONS CONTAINING ALLIUM SATIVUM LINN. (GARLIC) NATURALLY ENRICHED WITH ORGANIC SELENIUM COMPOUNDS FOR NUTRITIONAL SUPPLEMENTATION SAMI LABS LIMITED 2006-10-26 US disclosed
WO-2005023274-A1 TREATMENT AND PREVENTION OF INFLAMMATORY DISEASE AND MITOCHONDRIAL DYSFUNCTION WITH HIGH DOSE SELENIUM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2005-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108695-A1 COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING TUBERCULOSIS AND MRSA GGT1, GPX1, GCLC MAPT 410/4885CACNA1B 4482/4885APBA1 2695/4885
US-20240115666-A1 COMPOSITIONS AND METHODS FOR REDUCING GAMMA-GLUTAMYLTRANSFERASE LEVELS GGT1, GGCT, TGM2 MAPT 477/4885CACNA1B 4695/4885APBA1 2653/4885
US-20240108682-A1 COMPOSITIONS AND METHODS FOR INCREASING GLUTATHIONE LEVELS GGT1, GPX1, GSS MAPT 555/4885CACNA1B 4633/4885APBA1 2851/4885
US-20240108696-A1 COMPOSITIONS AND METHODS FOR IMPROVING VACCINE THERAPY GGT1, GPX1, TGM2 MAPT 347/4885CACNA1B 4456/4885APBA1 3003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.