SCHEMBL1707040

SCHEMBL1707040

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(=O)[nH]c(N(C)C)nc21

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.57
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
PAX8 Q06710 1/20 0.49
IMPDH2 P12268 1/20 0.48
IMPDH1 P20839 1/20 0.48
ADORA2A P29274 4/20 0.47
ADORA2B P29275 2/20 0.47
HINT1 P49773 1/20 0.47
ADORA3 P0DMS8 3/20 0.45
ADORA1 P30542 3/20 0.45
TAS1R3 Q7RTX0 1/20 0.44
TAS1R1 Q7RTX1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7246469 1.00 HPGD (0.57) HPGDMEN1KMT2APAX8IMPDH2
SCHEMBL21831928 1.00 HPGD (0.57) HPGDMEN1KMT2APAX8IMPDH2
SCHEMBL5950289 0.92 HPGD (0.57) HPGDPAX8IMPDH2IMPDH1ADORA2A
SCHEMBL14946393 0.89 HPGD (0.72) HPGDPAX8IMPDH2IMPDH1ADORA2A
SCHEMBL18512870 0.89 HPGD (0.72) HPGDPAX8IMPDH2IMPDH1ADORA2A
SCHEMBL40775 0.89 HPGD (0.72) HPGDPAX8IMPDH2IMPDH1ADORA2A
SCHEMBL18512872 0.89 HPGD (0.72) HPGDPAX8IMPDH2IMPDH1ADORA2A
SCHEMBL387030 0.89 HPGD (0.72) HPGDPAX8IMPDH2IMPDH1ADORA2A
SCHEMBL14929339 0.89 HPGD (0.72) HPGDPAX8IMPDH2IMPDH1ADORA2A
SCHEMBL25101150 0.88 HPGD (0.70) HPGDPAX8IMPDH2IMPDH1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
WO-2025137275-A1 NOVEL CAS NUCLEASES AND POLYNUCLEOTIDES ENCODING THE SAME MODERNATX, INC. (US) 2025-06-26 WO claimed
EP-4565692-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-06-11 EP claimed
EP-4486909-A2 RNA MOLECULE Imperial College Innovations Limited (GB) 2025-01-08 EP claimed
US-20240279676-A1 CONSTRUCTS AND METHODS FOR PREPARING CIRCULAR RNAS AND USE THEREOF Shanghai Circode Biomed Co., Ltd. (CN) 2024-08-22 US claimed
WO-2024129779-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-06-20 WO claimed
EP-4379052-A2 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION Ethris GmbH (DE) 2024-06-05 EP claimed
WO-2024031087-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-02-08 WO claimed
WO-2023215498-A2 COMPOSITIONS AND METHODS FOR CD28 ANTAGONISM MODERNATX, INC. (US) 2023-11-09 WO claimed
WO-2023166314-A2 RNA MOLECULE IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2023-09-07 WO claimed
US-20220195424-A1 Chemical Capping for Template Switching NEW ENGLAND BIOLABS, INC. (US) 2022-06-23 US claimed
US-9249473-B2 Compositions and methods for the identification of inhibitors of retroviral infection Trana Discover, Inc. (US) 2016-02-02 US claimed
US-20140121124-A1 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION GUENTHER RICHARD H (US) 2014-05-01 US claimed
EP-2201118-B1 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION TRANA DISCOVERY (US) 2012-04-18 EP claimed
US-20100291032-A1 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION TRANA DISCOVERY (US) 2010-11-18 US claimed
EP-2201118-A2 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION Trana Discovery (US) 2010-06-30 EP claimed
WO-2009036299-A2 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION TRANA DISCOVERY (US) 2009-03-19 WO claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS MODERNATX, INC. (US) 2026-05-28 US disclosed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100291032-A1 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION TRMT1L, TRMT1, TARBP1 HPGD 4622/4885MEN1 4421/4885KMT2A 2125/4885
US-20030007961-A1 Orthomolecular vitamin E derivatives RBP4, RBP1, VDR HPGD 1011/4885MEN1 3493/4885KMT2A 4864/4885
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS ELAVL1, IGF2BP2, FUS HPGD 4847/4885MEN1 3907/4885KMT2A 3684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.