Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RORC | P51449 | 7/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | RORA | P35398 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | RORB | Q92753 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064137 | 1.00 | MEN1 (0.62) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL10178084 | 0.88 | HTR6 (0.54) | MEN1KMT2ATP53MAPTRORC | |
| SCHEMBL13302143 | 0.83 | MAPT (0.54) | MEN1KMT2AMAPTRORCHTR6 | |
| SCHEMBL17064153 | 0.83 | HTR6 (0.57) | MEN1KMT2AMAPTRORCHTR6 | |
| SCHEMBL12053364 | 0.80 | MEN1 (0.73) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL29249701 | 0.78 | MEN1 (0.52) | MEN1KMT2ARORCNR1I2RORA | |
| SCHEMBL25073172 | 0.77 | RORC (0.64) | MEN1KMT2ATP53RORCNR1I2 | |
| SCHEMBL2692159 | 0.77 | KMT2A (1.00) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL13495474 | 0.76 | HTR6 (0.49) | MEN1KMT2ALMNAMAPTRORC | |
| SCHEMBL13495466 | 0.76 | MEN1 (0.47) | MEN1KMT2ALMNAMAPTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957231-B2 | Iodine(II)-mediated radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160362375-A1 | Iodine(III)-Mediated Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2016-12-15 | — | — | US | disclosed |
| US-9434699-B2 | Iodine(III)-mediated radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2016-09-06 | — | — | US | disclosed |
| US-20150252007-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252007-A1 | IODINE(III)-MEDIATED RADIOFLUORINATION | TPO, FLI1, SSTR3 | MEN1 183/4885KMT2A 1626/4885LMNA 2586/4885 |
| US-20160362375-A1 | Iodine(III)-Mediated Radiofluorination | TPO, FLI1, SSTR3 | MEN1 183/4885KMT2A 1626/4885LMNA 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.