SCHEMBL17070833

SCHEMBL17070833

CC(C)(C)c1ccc(OP(Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c2ccc(-c3ccc([PH](O)(Oc4ccc(C(C)(C)C)cc4C(C)(C)C)Oc4ccc(C(C)(C)C)cc4C(C)(C)C)cc3)cc2)c(C(C)(C)C)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32659992 0.86 APEX1 (0.34) APEX1
SCHEMBL205802 0.86 CA1 (0.35) APEX1
SCHEMBL29355846 0.86 CA1 (0.35) APEX1
SCHEMBL7621153 0.82 CA1 (0.33) APEX1
SCHEMBL29939280 0.82 CA1 (0.38) APEX1
SCHEMBL9298561 0.82 CA1 (0.38) APEX1
SCHEMBL24882673 0.81 TRPV1 (0.35) APEX1
SCHEMBL7640004 0.81 APEX1 (0.32) APEX1
SCHEMBL1132092 0.81 APEX1 (0.36) APEX1
SCHEMBL13259674 0.81 CA1 (0.35) APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150252066-A1 Process For Preparing A Polypropylene-Based Object Having An Increased Surface Energy CLAIRANT FINANCE (BVI) LIMITED (VG) 2015-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252066-A1 Process For Preparing A Polypropylene-Based Object Having An Increased Surface Energy PPOX, GPX4, NFE2L2 APEX1 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.