Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707646 | 0.95 | ROCK2 (0.40) | PDPK1ABCC1ALDH1A1POLBCCR3 | |
| SCHEMBL1707074 | 0.91 | SIGMAR1 (0.40) | PDPK1KCNH2DRD2DRD3SIGMAR1 | |
| SCHEMBL1707075 | 0.91 | SIGMAR1 (0.40) | PDPK1KCNH2DRD2DRD3SIGMAR1 | |
| SCHEMBL1706845 | 0.89 | ATM (0.40) | SIGMAR1HTR2A | |
| SCHEMBL1706846 | 0.89 | ATM (0.40) | SIGMAR1HTR2A | |
| SCHEMBL1708503 | 0.89 | HDAC1 (0.39) | PDPK1KCNH2DRD2DRD3SIGMAR1 | |
| SCHEMBL1708505 | 0.89 | HDAC1 (0.39) | PDPK1KCNH2DRD2DRD3SIGMAR1 | |
| SCHEMBL1706904 | 0.89 | JAK2 (0.41) | EED | |
| Hydrochloric Acid SCHEMBL1706849 | 0.88 | HDAC1 (0.38) | PDPK1KCNH2DRD2DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1706853 | 0.88 | HDAC1 (0.38) | PDPK1KCNH2DRD2DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |