Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706845 | 1.00 | ATM (0.40) | ATMCACNA1GOPRM1HTR2ASIGMAR1 | |
| SCHEMBL1707751 | 0.95 | SLC6A3 (0.41) | ATMCACNA1GHTR2ACCNT1SLC6A3 | |
| SCHEMBL1707312 | 0.91 | OPRM1 (0.42) | ATMCACNA1GOPRM1SIGMAR1SLC6A3 | |
| SCHEMBL1707309 | 0.91 | OPRM1 (0.42) | ATMCACNA1GOPRM1SIGMAR1SLC6A3 | |
| SCHEMBL1707677 | 0.89 | HDAC1 (0.42) | ATMCACNA1GOPRM1HTR2ASIGMAR1 | |
| SCHEMBL1707428 | 0.89 | PDPK1 (0.37) | HTR2ASIGMAR1 | |
| SCHEMBL1707679 | 0.89 | HDAC1 (0.42) | ATMCACNA1GOPRM1HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL1707198 | 0.88 | HDAC1 (0.41) | ATMCACNA1GOPRM1HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL1707202 | 0.88 | HDAC1 (0.41) | ATMCACNA1GOPRM1HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL1707307 | 0.88 | HDAC1 (0.41) | ATMCACNA1GOPRM1HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |