SCHEMBL2331880

SCHEMBL2331880

O=C(O)CCCCCCCCCNC(=O)c1ccccc1O.[NaH].[NaH]

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.68
ALDH1A1 P00352 2/20 0.64
HTT P42858 2/20 0.64
NPC1 O15118 1/20 0.64
MAPT P10636 1/20 0.64
HPGD P15428 1/20 0.64
TSHR P16473 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
HSD17B10 Q99714 1/20 0.64
NLRP1 Q9C000 1/20 0.64
ALOX5 P09917 1/20 0.62
MAPK1 P28482 1/20 0.59
NAMPT P43490 1/20 0.58
HDAC7 Q8WUI4 1/20 0.55
NR1H4 Q96RI1 2/20 0.54
KDM4E B2RXH2 1/20 0.54
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salcaprozic Acid SCHEMBL28397141 1.00 NAAA (0.68) NAAAALDH1A1HTTNPC1MAPT
Salcaprozic Acid SCHEMBL2159928 1.00 NAAA (0.68) NAAAALDH1A1HTTNPC1MAPT
SCHEMBL14088979 0.98 NAAA (0.70) NAAAALDH1A1HTTNPC1MAPT
SCHEMBL6383063 0.98 NAAA (0.70) NAAAALDH1A1HTTNPC1MAPT
SCHEMBL14088978 0.98 NAAA (0.70) NAAAALDH1A1HTTNPC1MAPT
Salcaprozic Acid SCHEMBL4586235 0.98 NAAA (0.70) NAAAALDH1A1HTTNPC1MAPT
SCHEMBL2331916 0.98 NAAA (0.70) NAAAALDH1A1HTTNPC1MAPT
SCHEMBL664024 0.98 NAAA (0.70) NAAAALDH1A1HTTNPC1MAPT
SCHEMBL13593340 0.98 NAAA (0.70) NAAAALDH1A1HTTNPC1MAPT
Salcaprozic Acid SCHEMBL29385752 0.98 NAAA (0.70) NAAAALDH1A1HTTNPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8658695-B2 Disodium salts, monohydrates, and ethanol solvates for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2014-02-25 US disclosed
US-20120264834-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS NOVARTIS AG (CH) 2012-10-18 US disclosed
US-8207227-B2 Disodium salts, monohydrates, and ethanol solvates for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2012-06-26 US disclosed
US-20110251125-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS NOVARTIS AG (CH) 2011-10-13 US disclosed
US-8003697-B2 Disodium salts, monohydrates, and ethanol solvates for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2011-08-23 US disclosed
US-20100099621-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2010-04-22 US disclosed
US-7659311-B2 Disodium salts, monohydrates, and ethanol solvates for delivering active agents NOVARTIS AG (CH) 2010-02-09 US disclosed
US-20080269134-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2008-10-30 US disclosed
US-7384982-B2 Disodium salts, monohydrates, and ethanol solvates for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2008-06-10 US disclosed
EP-1535625-A1 Composition containing n-(5-chlorosalicyloyl)-8-aminocaprylic acid and salmon calcitonin Emisphere Technologies, Inc. (US) 2005-06-01 EP disclosed
EP-1175390-B1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES EMISPHERE TECH INC (US) 2005-02-02 EP disclosed
US-20040106825-A1 Disodium salts, monohydrates, and ethanol solvates for delivering active agents EMISPHERE TECHNOLOGIES, INC. 2004-06-03 US disclosed
EP-1175390-A4 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES EMISPHERE TECH INC (US) 2002-09-04 EP disclosed
US-20020065255-A1 Disodium salts, monohydrates, and ethanol solvates for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2002-05-30 US disclosed
EP-1175390-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES Emisphere Technologies, Inc. (US) 2002-01-30 EP disclosed
WO-2000059863-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES EMISPHERE TECHNOLOGIES, INC. (US) 2000-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065255-A1 Disodium salts, monohydrates, and ethanol solvates for delivering active agents ADH1C, CLIC1, SLC9A1 NAAA 256/4885ALDH1A1 573/4885HTT 682/4885
US-20110251125-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADH1C, HCAR3 NAAA 141/4885ALDH1A1 928/4885HTT 357/4885
US-20080269134-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS HCAR3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADH1C NAAA 133/4885ALDH1A1 999/4885HTT 403/4885
US-20120264834-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS ACMSD, SLC38A7, SLC10A1 NAAA 111/4885ALDH1A1 709/4885HTT 414/4885
US-20100099621-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS HCAR3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADH1C NAAA 133/4885ALDH1A1 999/4885HTT 403/4885
US-20040106825-A1 Disodium salts, monohydrates, and ethanol solvates for delivering active agents ADH1C, CLIC1, SLC9A1 NAAA 256/4885ALDH1A1 573/4885HTT 682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.