SCHEMBL1707504

SCHEMBL1707504

Nc1ccc(NC(=O)CCl)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.63
NPC1 O15118 3/20 0.63
MITF O75030 2/20 0.63
XBP1 P17861 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
NOD2 Q9HC29 1/20 0.63
ALDH1A1 P00352 9/20 0.61
SMN1; SMN2 Q16637 7/20 0.61
HTT P42858 5/20 0.61
PRMT1 Q99873 1/20 0.61
MAPT P10636 8/20 0.59
KMT2A Q03164 6/20 0.57
MEN1 O00255 4/20 0.57
LMNA P02545 5/20 0.56
KDM4E B2RXH2 2/20 0.56
RNF4 P78317 1/20 0.56
PKM P14618 2/20 0.53
POLB P06746 1/20 0.53
APEX1 P27695 1/20 0.53
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9081388 0.89 NPC1 (0.76) RAB9ANPC1MITFXBP1NPSR1
4-Nitroaniline SCHEMBL3978656 0.85 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2HTTPRMT1MAPT
SCHEMBL11417562 0.84 MAPT (0.55) RAB9ANPC1MITFXBP1NPSR1
SCHEMBL15197080 0.83 MAPT (0.64) RAB9ASMN1; SMN2MAPTKMT2AMEN1
SCHEMBL11717080 0.81 MAPT (0.61) RAB9ANPC1ALDH1A1SMN1; SMN2MAPT
SCHEMBL2635734 0.81 NPC1 (0.66) RAB9ANPC1MITFXBP1NPSR1
SCHEMBL11717085 0.81 MAPT (0.61) RAB9ANPC1ALDH1A1SMN1; SMN2MAPT
SCHEMBL16922181 0.81 NPC1 (0.66) RAB9ANPC1MITFXBP1NPSR1
SCHEMBL6934242 0.81 RAB9A (0.61) RAB9ANPC1SMN1; SMN2MAPTKMT2A
SCHEMBL1503954 0.81 NPC1 (0.66) RAB9ANPC1MITFXBP1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285558-A Novel GSDMD inhibitor and preparation method and application thereof 四川大学 2025-01-10 CN disclosed
CN-109265451-B Butyrylcholinesterase selective inhibitor and preparation method and application thereof 中国药科大学 2022-07-15 CN disclosed
EP-3771687-A1 REVERSIBLE PHOTO-CONTROLLED FRAC NANOPORES, MODIFIED FRAC MONOMERS, METHODS FOR PREPARING THE SAME, AND USES THEREOF RIJKSUNIVERSITEIT GRONINGEN (NL) 2021-02-03 EP disclosed
CN-109575463-A A kind of preparation method of mobile phone screen protector 李佳峻 2019-04-05 CN disclosed
EP-1478696-B1 PROCESS FOR THE PREPARATION OF CATIONIC AZO COMPOUNDS BASF SE (DE) 2012-04-18 EP disclosed
EP-0352222-B1 Fibre-reactive formazane dyes, process for their preparation and their use CIBA GEIGY AG (CH) 1994-05-25 EP disclosed
US-5114430-A Colorfast dyes that react with fibers to form red, orange or red color CIBA-GEIGY CORPORATION (US) 1992-05-19 US disclosed
US-4994562-A Colorfast; for dyeing wool, silk CIBA-GEIGY CORPORATION (US) 1991-02-19 US disclosed
EP-0352222-A2 Fibre-reactive formazane dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1990-01-24 EP disclosed
US-4742160-A CATIONIC DYES; PRINTING SANDOZ LTD. (CH) 1988-05-03 US disclosed
US-4340531-A Aqueous-media dispersible, highly-concentrated, finely-disperse, low-dispersant or free-of-dispersant preparation of hardly water-soluble to water-insoluble active substances in solid form, process for their preparation and their application ROHNER AG PRATTELN (CH) 1982-07-20 US disclosed
US-4286962-A Phthalocyanine reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl groups or amide groups BAYER AKTIENGESELLSCHAFT (DE) 1981-09-01 US disclosed
US-4267107-A WATER SOLUBLE PHTHALOCYANINE DYES BAYER AKTIENGESELLSCHAFT (DE) 1981-05-12 US disclosed
US-4220586-A FASTNESS TO LIGHT, OVER-LACQUERING, MIGRATION, WEATHERING, AND HEAT CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
EP-0014318-A1 Reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups BAYER AG (DE) 1980-08-20 EP disclosed
US-4213898-A FOR POLYACRYLONITRILE SANDOZ LTD. (CH) 1980-07-22 US disclosed
US-4094636-A DIAZOTIZATION HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4080321-A COLORFASTNESS HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-21 US disclosed
US-4038240-A PROCESS FOR DYEING POLYURETHANE RESINS BAYER AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed