Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917257 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL3156871 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| Heptane SCHEMBL17076906 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| Heptane SCHEMBL17076924 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| Heptane SCHEMBL17076872 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL15189290 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL6065522 | 1.00 | TSHR (0.44) | TSHRTHRBLMNADNM1OPRM1 | |
| Phosphine SCHEMBL19411938 | 0.97 | LMNA (0.42) | TSHRTHRBLMNADNM1OPRM1 | |
| Ammonia Solution, Strong SCHEMBL7229632 | 0.97 | LMNA (0.42) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL3602893 | 0.97 | OPRM1 (0.43) | TSHRTHRBLMNADNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822707-B2 | Nucleophile assisting leaving groups | FLORIDA ATLANTIC UNIVERSITY (US) | 2014-09-02 | — | — | US | disclosed |
| US-20080221347-A1 | Oligoether, crown ether linked to an acyclic or cyclic group linked with a sulfonate or silanol leaving group to an alkyl group, an alkenyl group, an alkynyl group or an optionally substituted aromatic or heteroaryl group; stabilized leaving group is more easily displaced | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-11 | — | — | US | disclosed |
| WO-2006060142-A2 | NUCLEOPHILE ASSISTING LEAVING GROUPS | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-06-08 | — | — | WO | disclosed |
| US-6809206-B2 | CONTACTING A PHENYL ESTER COMPOUND WITH A CYCLIC COMPOUND IN THE PRESENCE OF A SOURCE OF CYANIDE OR FLUORIDE TO PREPARE ACYLATED CYCLIC 1,3-DICARBONYL COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-10-26 | — | — | US | disclosed |
| WO-2003040083-A1 | ENANTIOSELECTIVE HYDROXYLATION OF BETA-DICARBONYLS CATALYZED BY CINCHONA ALKALOID DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-0652876-A1 | HERBICIDAL TRIAZINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994003454-A1 | HERBICIDAL TRIAZINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-17 | — | — | WO | disclosed |
| EP-0336587-B1 | FLUOROALKOXY AMINO TRIAZINES FOR CONTROL OF WEEDS IN SUGAR BEETS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-11 | — | — | EP | disclosed |
| EP-0523067-A1 | CROP-SELECTIVE HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5090993-A | Herbicides, plant growth regulators | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0404758-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4878937-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-07 | — | — | US | disclosed |
| EP-0336587-A1 | Fluoroalkoxy amino triazines for control of weeds in sugar beets | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-11 | — | — | EP | disclosed |
| WO-1989009214-A1 | FLUOROALKOXY AMINO TRIAZINES FOR CONTROL OF WEEDS IN SUGAR BEETS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-05 | — | — | WO | disclosed |
| EP-0404758-A4 | HERBICIDAL SULFONAMIDES. | DU PONT (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4854962-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4752322-A | Herbicidal sulfonamides | DUMAS DONALD J (US) | 1988-06-21 | — | — | US | disclosed |
| US-4746356-A | Herbicidal sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| WO-1987007114-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-03 | — | — | WO | disclosed |
| US-4017529-A | Herbicidal allophanimidates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221347-A1 | Oligoether, crown ether linked to an acyclic or cyclic group linked with a sulfonate or silanol leaving group to an alkyl group, an alkenyl group, an alkynyl group or an optionally substituted aromatic or heteroaryl group; stabilized leaving group is more easily displaced | OSTC, STS, TST | TSHR 722/4885THRB 1401/4885LMNA 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.