Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17076873 | 0.83 | RPS6KA2 (0.32) | — | |
| SCHEMBL19763398 | 0.83 | MAOA (0.34) | PGRMAOAMAPTALDH1A1PPARG | |
| SCHEMBL17085384 | 0.79 | MAOA (0.54) | MAOAMAPTALDH1A1LMNANPC1 | |
| SCHEMBL20198704 | 0.76 | MAOA (0.40) | PGRMAOAMAPTALDH1A1LMNA | |
| SCHEMBL3830596 | 0.72 | MAOA (0.46) | MAOAMAPTALDH1A1LMNANPC1 | |
| SCHEMBL19836207 | 0.71 | PGR (0.43) | PGRMAOAMAPTALDH1A1PPARG | |
| SCHEMBL31336207 | 0.70 | ABCG2 (0.37) | MAOAALDH1A1LMNANPC1RAB9A | |
| SCHEMBL19443962 | 0.69 | MAPT (0.35) | MAPTALDH1A1LMNARAB9AKDM4E | |
| SCHEMBL19763397 | 0.68 | — | — | |
| SCHEMBL22233752 | 0.67 | AHR (0.51) | PGRMAOAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926765-B | 4, 6-difluorodibenzofuran derivatives | 默克专利股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-20210284911-A1 | Electro-Optical Display Elements | MERCK PATENT GMBH (DE) | 2021-09-16 | — | — | US | disclosed |
| US-11060029-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-07-13 | — | — | US | disclosed |
| US-10883047-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-01-05 | — | — | US | disclosed |
| EP-3541892-B1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |
| US-10774263-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2020-09-15 | — | — | US | disclosed |
| EP-3677659-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2020-07-08 | — | — | EP | disclosed |
| EP-3460025-B1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-3081620-B1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |
| EP-3327011-B1 | 4,6-DIFLUOR-DIBENZOFURANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-03-25 | — | — | EP | disclosed |
| EP-3081620-A2 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2016-10-19 | — | — | EP | disclosed |
| US-20160298033-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160298033-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160090533-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | US | disclosed |
| US-20160090533-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | US | disclosed |
| WO-2015139827-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | WO | disclosed |
| EP-2921487-A1 | 4,6-Difluoro-dibenzofurans | Merck Patent GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-20150259602-A1 | 4,6-DIFLUORODIBENZOFURAN DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20150259602-A1 | 4,6-DIFLUORODIBENZOFURAN DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
| US-20150259602-A1 | 4,6-DIFLUORODIBENZOFURAN DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090533-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, FES, RAP2C | PGR 1976/4885MAOA 1994/4885MAPT 2257/4885 |
| US-20210284911-A1 | Electro-Optical Display Elements | VCL, CASK, SDF4 | PGR 2613/4885MAOA 2942/4885MAPT 3527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.