Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707747 | 0.83 | FFAR1 (0.42) | — | |
| SCHEMBL3716544 | 0.82 | HTR2A (0.33) | MAPTALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL3719338 | 0.79 | FFAR1 (0.37) | MAPTALDH1A1MAPK1CD274 | |
| SCHEMBL1707925 | 0.79 | MAPT (0.36) | MAPTALDH1A1MAPK1CD274POLB | |
| SCHEMBL3798510 | 0.78 | ALDH1A1 (0.33) | MAPTALDH1A1MAPK1 | |
| SCHEMBL1707930 | 0.78 | MAPT (0.36) | MAPTALDH1A1MAPK1CD274POLB | |
| SCHEMBL1708185 | 0.77 | ALDH1A1 (0.37) | MAPTALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL1708320 | 0.77 | FFAR1 (0.38) | MAPTALDH1A1MAPK1CD274 | |
| SCHEMBL3718225 | 0.77 | FFAR1 (0.37) | MAPTALDH1A1MAPK1CD274 | |
| SCHEMBL1707964 | 0.77 | INSR (0.36) | MAPTALDH1A1CD274MAPK14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |