Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707930 | 0.99 | MAPT (0.36) | MAPTALDH1A1MAPK1USP2MEN1 | |
| SCHEMBL1708185 | 0.94 | ALDH1A1 (0.37) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1708215 | 0.93 | ALDH1A1 (0.36) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1707924 | 0.84 | FFAR1 (0.40) | — | |
| SCHEMBL1707929 | 0.83 | FFAR1 (0.33) | MAPTALDH1A1MAPK1USP2MEN1 | |
| SCHEMBL3798510 | 0.81 | ALDH1A1 (0.33) | MAPTALDH1A1MAPK1 | |
| SCHEMBL1707916 | 0.80 | MTOR (0.36) | MAPTALDH1A1MAPK1USP2MEN1 | |
| SCHEMBL1708449 | 0.79 | FFAR1 (0.38) | — | |
| SCHEMBL13047337 | 0.79 | FFAR1 (0.37) | MAPTALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL1707749 | 0.79 | MAPT (0.34) | MAPTALDH1A1MAPK1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |