Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 14/20 | 0.34 |
| ▸ | RAF1 | P04049 | 12/20 | 0.34 |
| ▸ | STAT6 | P42226 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708457 | 0.93 | STAT6 (0.37) | GAAALOX15MAPK1BRAFRAF1 | |
| SCHEMBL1707869 | 0.92 | STAT6 (0.36) | GAAALOX15MAPK1BRAFRAF1 | |
| SCHEMBL1708223 | 0.87 | FFAR1 (0.42) | GAASTAT6 | |
| SCHEMBL3715118 | 0.82 | PTGES (0.39) | — | |
| SCHEMBL3719582 | 0.81 | WNT3A (0.39) | GAAALOX15MAPK1BRAFRAF1 | |
| SCHEMBL1708222 | 0.81 | STAT6 (0.36) | GAAALOX15MAPK1BRAFRAF1 | |
| SCHEMBL13046563 | 0.81 | FFAR1 (0.40) | GAAALOX15MAPK1STAT6 | |
| SCHEMBL1708456 | 0.80 | FFAR1 (0.45) | STAT6 | |
| SCHEMBL1707868 | 0.79 | FFAR1 (0.38) | GAAALOX15MAPK1BRAFRAF1 | |
| SCHEMBL10292319 | 0.78 | FFAR1 (0.36) | GAAALOX15MAPK1BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |