SCHEMBL1707907

SCHEMBL1707907

CC(=O)NCCNC(=O)CC(=O)OCCOc1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MTNR1A P48039 3/20 0.46
MTNR1B P49286 3/20 0.46
ALDH1A1 P00352 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.43
ACACB O00763 1/20 0.41
MAPT P10636 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838367 0.95 MAPT (0.44) USP2ALOX15TSHRMAPK1HSD17B10
SCHEMBL4758832 0.93 USP2 (0.41) USP2ALOX15TSHRMAPK1HSD17B10
SCHEMBL402847 0.92 MAPT (0.41) USP2ALOX15TSHRMAPK1HSD17B10
SCHEMBL10029314 0.92 MAPT (0.44) USP2ALOX15TSHRMAPK1HSD17B10
SCHEMBL838083 0.91 MAPT (0.49) TSHRALDH1A1L3MBTL1MAPTPOLB
SCHEMBL14369609 0.91 SMN1; SMN2 (0.46) MAPK1ALDH1A1L3MBTL1MAPTMEN1
SCHEMBL10030725 0.91 USP2 (0.41) USP2ALOX15TSHRMAPK1HSD17B10
SCHEMBL12091364 0.91 MAPT (0.43) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL4747310 0.91 MAPT (0.40) USP2ALOX15TSHRMAPK1HSD17B10
SCHEMBL401764 0.91 RECQL (0.47) MTNR1AACACBMAPTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8657430-B2 Curable phase change inks containing crystalline polyesters XEROX CORPORATION (US) 2014-02-25 US disclosed
US-8652574-B2 Ink compositions XEROX CORPORATION (US) 2014-02-18 US disclosed
US-20120086761-A1 CURABLE PHASE CHANGE INKS CONTAINING CRYSTALLINE POLYESTERS XEROX CORPORATION (US) 2012-04-12 US disclosed
US-20110177246-A1 INK COMPOSITIONS XEROX CORPORATION (US) 2011-07-21 US disclosed
US-7954430-B2 Underside curing of radiation curable inks XEROX CORPORATION (US) 2011-06-07 US disclosed
US-7905948-B2 Phase change ink compositions XEROX CORPORATION (US) 2011-03-15 US disclosed
US-20090135239-A1 UNDERSIDE CURING OF RADIATION CURABLE INKS XEROX CORPORATION (US) 2009-05-28 US disclosed
US-20090046134-A1 Phase change ink compositions XEROX CORPORATION 2009-02-19 US disclosed