SCHEMBL17080321

SCHEMBL17080321

O=C(OC1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)C(O)CO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ GAA P10253 1/20 0.42
▸ TYR P14679 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ LGALS1 P09382 2/20 0.42
▸ LGALS3 P17931 2/20 0.42
▸ PRKD3 O94806 1/20 0.42
▸ PRKCG P05129 1/20 0.42
▸ PRKCB P05771 1/20 0.42
▸ PRKCA P17252 1/20 0.42
▸ PRKCH P24723 1/20 0.42
▸ PRKCI P41743 1/20 0.42
▸ PRKCE Q02156 1/20 0.42
▸ PRKCQ Q04759 1/20 0.42
▸ PRKCZ Q05513 1/20 0.42
▸ PRKCD Q05655 1/20 0.42
▸ PRKD1 Q15139 1/20 0.42
▸ LGALS9 O00182 1/20 0.42
▸ LGALS8 O00214 1/20 0.42
▸ PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28770797 1.00 L3MBTL1 (0.43) L3MBTL1GAATYRMAPTLGALS1
SCHEMBL28114439 1.00 L3MBTL1 (0.43) L3MBTL1GAATYRMAPTLGALS1
SCHEMBL9544906 1.00 L3MBTL1 (0.43) L3MBTL1GAATYRMAPTLGALS1
SCHEMBL27918710 1.00 L3MBTL1 (0.43) L3MBTL1GAATYRMAPTLGALS1
SCHEMBL10319429 1.00 L3MBTL1 (0.43) L3MBTL1GAATYRMAPTLGALS1
SCHEMBL4766863 0.89 ALDH1A1 (0.45) L3MBTL1GAAMAPTSLC28A3PYGB
SCHEMBL19742822 0.88 PRKD3 (0.41) L3MBTL1GAATYRMAPTPRKD3
SCHEMBL28909065 0.88 SYNJ2 (0.48) L3MBTL1GAATYRMAPTPRKD3
SCHEMBL4771457 0.88 SYNJ2 (0.43) L3MBTL1GAAMAPTSLC28A3PYGB
SCHEMBL17080337 0.88 SYNJ2 (0.48) L3MBTL1GAATYRMAPTPRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590117-B2 Hexose derivatives, preparation and uses thereof FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) 2026-03-31 — — US disclosed
US-20230357301-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) 2023-11-09 — — US disclosed
US-11708387-B2 Hexose derivatives, preparation and uses thereof FACULDADE DE CIÊNCIAS DA UNIVERSIDADE DE LISBOA (PT) 2023-07-25 — — US disclosed
CN-115448964-A Hexose derivatives and their formulations and use 里斯本大学科学与技术学院 2022-12-09 — — CN disclosed
US-20180170955-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF UNIVERSIDADE NOVA DE LISBOA (PT) 2018-06-21 — — US disclosed
EP-3116886-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF Faculdade De Ciências da Universidade de Lisboa (PT) 2017-01-18 — — EP disclosed
WO-2015137838-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF EXTREMOCHEM, LDA. (PT) 2015-09-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180170955-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF HK1, SLC5A1, HK2 L3MBTL1 3975/4885GAA 1568/4885TYR 835/4885
US-20230357301-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF HK1, SLC5A1, HK2 L3MBTL1 3975/4885GAA 1568/4885TYR 835/4885
US-12590117-B2 Hexose derivatives, preparation and uses thereof SLC5A1, HK1, SLC5A2 L3MBTL1 4199/4885GAA 2176/4885TYR 1050/4885
US-11708387-B2 Hexose derivatives, preparation and uses thereof HK1, SLC5A1, HK2 L3MBTL1 3975/4885GAA 1568/4885TYR 835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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