SCHEMBL17080337

SCHEMBL17080337

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nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SYNJ2 O15056 2/20 0.48
▸ GAA P10253 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ ABL1 P00519 1/20 0.48
▸ ALPL P05186 1/20 0.48
▸ POLB P06746 1/20 0.48
▸ ALPI P09923 1/20 0.48
▸ ALPG P10696 1/20 0.48
▸ PABPC1 P11940 1/20 0.48
▸ RECQL P46063 1/20 0.48
▸ GALK1 P51570 1/20 0.48
▸ CASP7 P55210 1/20 0.48
▸ CASP6 P55212 1/20 0.48
▸ MCL1 Q07820 1/20 0.48
▸ RIN1 Q13671 1/20 0.48
▸ EIF4H Q15056 1/20 0.48
▸ KDR P35968 1/20 0.44
▸ LGALS8 O00214 1/20 0.41
▸ IGF2R P11717 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28909065 1.00 SYNJ2 (0.48) SYNJ2GAAMAPTKDM4EABL1
SCHEMBL19742822 0.91 PRKD3 (0.41) SYNJ2GAAMAPTKDM4EABL1
SCHEMBL27918710 0.88 L3MBTL1 (0.43) SYNJ2GAAMAPTLGALS8L3MBTL1
SCHEMBL17080321 0.88 L3MBTL1 (0.43) SYNJ2GAAMAPTLGALS8L3MBTL1
SCHEMBL28114439 0.88 L3MBTL1 (0.43) SYNJ2GAAMAPTLGALS8L3MBTL1
SCHEMBL10319429 0.88 L3MBTL1 (0.43) SYNJ2GAAMAPTLGALS8L3MBTL1
SCHEMBL9544906 0.88 L3MBTL1 (0.43) SYNJ2GAAMAPTLGALS8L3MBTL1
SCHEMBL28770797 0.88 L3MBTL1 (0.43) SYNJ2GAAMAPTLGALS8L3MBTL1
SCHEMBL29603364 0.87 SYNJ2 (0.40) SYNJ2GAAMAPTKDM4EABL1
SCHEMBL4766863 0.84 ALDH1A1 (0.45) SYNJ2GAAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590117-B2 Hexose derivatives, preparation and uses thereof FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) 2026-03-31 — — US disclosed
US-20230357301-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA (PT) 2023-11-09 — — US disclosed
US-11708387-B2 Hexose derivatives, preparation and uses thereof FACULDADE DE CIÊNCIAS DA UNIVERSIDADE DE LISBOA (PT) 2023-07-25 — — US disclosed
CN-115448964-A Hexose derivatives and their formulations and use 里斯本大学科学与技术学院 2022-12-09 — — CN disclosed
US-20180170955-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF UNIVERSIDADE NOVA DE LISBOA (PT) 2018-06-21 — — US disclosed
EP-3116886-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF Faculdade De Ciências da Universidade de Lisboa (PT) 2017-01-18 — — EP disclosed
WO-2015137838-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF EXTREMOCHEM, LDA. (PT) 2015-09-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180170955-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF HK1, SLC5A1, HK2 SYNJ2 4597/4885GAA 1568/4885MAPT 4128/4885
US-20230357301-A1 HEXOSE DERIVATIVES, PREPARATION AND USES THEREOF HK1, SLC5A1, HK2 SYNJ2 4597/4885GAA 1568/4885MAPT 4128/4885
US-12590117-B2 Hexose derivatives, preparation and uses thereof SLC5A1, HK1, SLC5A2 SYNJ2 4174/4885GAA 2176/4885MAPT 4327/4885
US-11708387-B2 Hexose derivatives, preparation and uses thereof HK1, SLC5A1, HK2 SYNJ2 4597/4885GAA 1568/4885MAPT 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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