Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15999477 | 0.84 | ALDH1A1 (0.72) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL3587685 | 0.84 | LMNA (0.56) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL18532453 | 0.84 | LMNA (0.55) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL18532399 | 0.80 | LMNA (0.62) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL26033234 | 0.80 | LMNA (0.51) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL17080657 | 0.80 | POLB (0.43) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL12410537 | 0.78 | MEN1 (0.68) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17080656 | 0.76 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27199967 | 0.76 | KMT2A (0.59) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL16324795 | 0.76 | ALDH1A1 (0.67) | LMNAPOLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170000902-A1 | EGFR-TARGETED NANOPARTICLES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-01-05 | — | — | US | disclosed |
| US-9446149-B2 | Nanoparticles stabilized with nitrophenylboronic acid compositions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160000934-A1 | NANOPARTICLES STABILIZED WITH NITROPHENYLBORONIC ACID COMPOSITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| US-9132097-B2 | Nanoparticles stabilized with nitrophenylboronic acid compositions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000934-A1 | NANOPARTICLES STABILIZED WITH NITROPHENYLBORONIC ACID COMPOSITIONS | NCL, B3GNT2, NBAS | LMNA 653/4885POLB 832/4885ALDH1A1 2606/4885 |
| US-20170000902-A1 | EGFR-TARGETED NANOPARTICLES | EGFR, ERBB2, ERBB3 | LMNA 2532/4885POLB 3470/4885ALDH1A1 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.