Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15999478 | 0.85 | ALDH1A1 (0.58) | POLBLMNANPC1CYP3A4ALDH1A1 | |
| SCHEMBL17080658 | 0.80 | LMNA (0.55) | POLBLMNANPC1CYP3A4ALDH1A1 | |
| SCHEMBL18079540 | 0.75 | HPGD (0.58) | POLBALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL17080656 | 0.75 | LMNA (0.52) | LMNAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17998207 | 0.74 | HPGD (0.57) | NPC1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL3587685 | 0.74 | LMNA (0.56) | POLBLMNANPC1CYP3A4ALDH1A1 | |
| SCHEMBL20978673 | 0.73 | ALDH1A1 (0.39) | LMNANPC1CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL26757982 | 0.73 | KMT2A (0.51) | POLBLMNANPC1CYP3A4ALDH1A1 | |
| SCHEMBL16364997 | 0.72 | HPGD (0.53) | POLBLMNANPC1CYP3A4ALDH1A1 | |
| SCHEMBL1668197 | 0.72 | POLB (0.53) | POLBLMNANPC1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170000902-A1 | EGFR-TARGETED NANOPARTICLES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-01-05 | — | — | US | disclosed |
| US-9446149-B2 | Nanoparticles stabilized with nitrophenylboronic acid compositions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20160000934-A1 | NANOPARTICLES STABILIZED WITH NITROPHENYLBORONIC ACID COMPOSITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| US-9132097-B2 | Nanoparticles stabilized with nitrophenylboronic acid compositions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000934-A1 | NANOPARTICLES STABILIZED WITH NITROPHENYLBORONIC ACID COMPOSITIONS | NCL, B3GNT2, NBAS | POLB 832/4885LMNA 653/4885NPC1 191/4885 |
| US-20170000902-A1 | EGFR-TARGETED NANOPARTICLES | EGFR, ERBB2, ERBB3 | POLB 3470/4885LMNA 2532/4885NPC1 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.