Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.45 |
| ▸ | ELOC | Q15369 | 1/20 | 0.45 |
| ▸ | ELOB | Q15370 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843801 | 0.90 | MAOA (0.49) | VHLELOCELOBCYP2A6MAOA | |
| SCHEMBL27844098 | 0.90 | MAOA (0.49) | VHLELOCELOBCYP2A6MAOA | |
| SCHEMBL31029247 | 0.79 | CASP1 (0.59) | VHLELOCELOBPBRM1CASP1 | |
| SCHEMBL1151032 | 0.79 | PBRM1 (0.59) | VHLELOCELOBPBRM1CASP1 | |
| SCHEMBL6940637 | 0.79 | CASP1 (0.52) | PBRM1CASP1CASP7HSD17B10PTGS2 | |
| SCHEMBL28603 | 0.79 | CASP1 (0.59) | VHLELOCELOBPBRM1CASP1 | |
| SCHEMBL30402712 | 0.79 | CASP1 (0.52) | PBRM1CASP1CASP7HSD17B10PTGS2 | |
| SCHEMBL29506179 | 0.79 | PBRM1 (0.59) | VHLELOCELOBPBRM1CASP1 | |
| Hydrochloric Acid SCHEMBL28688881 | 0.76 | CASP1 (0.55) | VHLELOCELOBCASP1CASP7 | |
| SCHEMBL27844072 | 0.75 | CYP2A6 (0.42) | VHLELOCELOBCYP2A6SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | BRUMMOND, KAY M | 2016-02-18 | — | — | US | disclosed |
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | BRUMMOND, KAY M | 2016-02-18 | — | — | US | disclosed |
| US-9133234-B2 | Functionalized naphthalene fluorophores | Brummond, Kay M. (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133234-B2 | Functionalized naphthalene fluorophores | Brummond, Kay M. (US) | 2015-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046666-A1 | FUNCTIONALIZED NAPHTHALENE FLUOROPHORES | NCL, SNW1, NEK1 | VHL 216/4885ELOC 793/4885ELOB 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.