Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | VHL | P40337 | 1/20 | 0.47 |
| ▸ | ELOC | Q15369 | 1/20 | 0.47 |
| ▸ | ELOB | Q15370 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029247 | 1.00 | CASP1 (0.59) | CASP1CASP7HSD17B10SRD5A1SRD5A2 | |
| Hydrochloric Acid SCHEMBL28688881 | 0.96 | CASP1 (0.55) | CASP1CASP7HSD17B10SRD5A1SRD5A2 | |
| Aluminum Chloride Anhydrous SCHEMBL28688879 | 0.94 | CASP1 (0.53) | CASP1CASP7HSD17B10SRD5A1SRD5A2 | |
| Acetic Acid SCHEMBL28550221 | 0.89 | SRD5A1 (0.58) | CASP1CASP7HSD17B10SRD5A1SRD5A2 | |
| SCHEMBL1798900 | 0.88 | MAOA (0.67) | CASP1CASP7HSD17B10SRD5A1SRD5A2 | |
| SCHEMBL5108894 | 0.88 | MAOA (0.61) | CASP1CASP7HSD17B10SRD5A1SRD5A2 | |
| Tetrahydrofuran SCHEMBL28740997 | 0.88 | SRD5A1 (0.49) | CASP1CASP7HSD17B10SRD5A1SRD5A2 | |
| Formic Acid Methyl Ester SCHEMBL28686517 | 0.86 | CASP1 (0.46) | CASP1CASP7HSD17B10SRD5A1SRD5A2 | |
| SCHEMBL2601324 | 0.84 | METAP1 (0.60) | SRD5A1SRD5A2HTTMETAP1VHL | |
| SCHEMBL1746656 | 0.84 | HSD17B1 (0.69) | CASP1CASP7HSD17B10SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 799 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042831-A1 | PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2025-02-06 | — | — | US | claimed |
| EP-4444690-A1 | PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2024-10-16 | — | — | EP | claimed |
| CN-118591521-A | Process for preparing 5-chloro-2, 3-dihydro-1H-inden-1-one | 安道麦马克西姆有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-117430489-A | Preparation method of 5-chloro-1-indenone | 山东京博生物科技有限公司 | 2024-01-23 | — | — | CN | claimed |
| WO-2023102721-A1 | PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2023-06-15 | — | — | WO | claimed |
| CN-115974664-A | Synthesis method of 5-chloro-1-indanone | 合肥工业大学 | 2023-04-18 | — | — | CN | claimed |
| CN-114105972-B | Cinchonine derivative and application thereof in preparation of high-optical-purity indoxacarb intermediate | 安徽广信农化股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-113861113-B | Preparation and application of fused ring pyridine compound and derivative thereof | 中国科学院福建物质结构研究所 | 2022-12-06 | — | — | CN | claimed |
| CN-113527075-B | Preparation method for synthesizing 5-chloro-1-indanone by one-step method | 佳尔科生物科技南通有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-111454137-B | Synthetic method for improving yield of 5-chloro-1-indanone | 山东京博生物科技有限公司 | 2022-09-23 | — | — | CN | claimed |
| US-20160332016-A1 | Fire Extinguishing Composition Comprising Aldoketones Compound | NANO FIRE, LLC | 2016-11-17 | — | — | US | claimed |
| US-9309165-B2 | 6-chloro-3-(phenyl-d5)-inden-1-one and use thereof | H. LUNDBECK A/S (DK) | 2016-04-12 | — | — | US | claimed |
| US-20150336867-A1 | 6-chloro-3-(phenyl-d5)-inden-1-one and use thereof | H. LUNDBECK A/S (DK) | 2015-11-26 | — | — | US | claimed |
| EP-2943460-A2 | 6-CHLORO-3-(PHENYL-D5)-INDEN-1-ONE AND USE THEREOF | H. Lundbeck A/S (DK) | 2015-11-18 | — | — | EP | claimed |
| WO-2014096151-A2 | 6-CHLORO-3-(PHENYL-D5)-INDEN-1-ONE AND USE THEREOF | H. LUNDBECK A/S (DK) | 2014-06-26 | — | — | WO | claimed |
| WO-2000043342-A1 | METHOD FOR PRODUCING A INDANONE OR THIOINDANONE TYPE COMPOUND | RHODIA CHIMIE (FR) | 2000-07-27 | — | — | WO | claimed |
| EP-0800500-B1 | A PROCESS FOR PREPARING 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE | DU PONT (US) | 1999-06-02 | — | — | EP | claimed |
| US-5811585-A | CONTACTING 3-CHLORO-1-/4-CHLOROPHENYL/-1-PROPANOL WITH ACID CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-09-22 | — | — | US | claimed |
| EP-0800500-A1 | A PROCESS FOR PREPARING 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-10-15 | — | — | EP | claimed |
| WO-1996020151-A1 | A PROCESS FOR PREPARING 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-07-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042831-A1 | PROCESS FOR PREPARING 5-CHLORO-2, 3-DIHYDRO-1H-INDEN-1-ONE | SI, IDO1, CYP4B1 | CASP1 978/4885CASP7 3553/4885HSD17B10 958/4885 |
| US-20150336867-A1 | 6-chloro-3-(phenyl-d5)-inden-1-one and use thereof | CYP2D6, UGT1A6, IDO1 | CASP1 1810/4885CASP7 1866/4885HSD17B10 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.