Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FSHR | P23945 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570221 | 1.00 | ROCK2 (0.32) | ROCK2PRKACAPRKACGPRKACBLIMK1 | |
| SCHEMBL10112699 | 0.94 | ROCK2 (0.35) | ROCK2PRKACAPRKACGPRKACBLIMK1 | |
| SCHEMBL17082191 | 0.91 | ALDH1A1 (0.36) | OGATSHRFSHRHSD11B1DHODH | |
| SCHEMBL17082137 | 0.91 | ALDH1A1 (0.36) | OGATSHRFSHRHSD11B1DHODH | |
| SCHEMBL4570219 | 0.91 | ALDH1A1 (0.36) | OGATSHRFSHRHSD11B1DHODH | |
| SCHEMBL4570147 | 0.91 | ALDH1A1 (0.36) | OGATSHRFSHRHSD11B1DHODH | |
| SCHEMBL17082119 | 0.91 | HCRTR2 (0.33) | TSHRFSHRHSD11B1 | |
| SCHEMBL17082115 | 0.91 | HCRTR2 (0.33) | TSHRFSHRHSD11B1 | |
| SCHEMBL4570217 | 0.91 | HCRTR2 (0.33) | TSHRFSHRHSD11B1 | |
| SCHEMBL4570186 | 0.91 | HCRTR2 (0.33) | TSHRFSHRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812005-B1 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2015-09-16 | — | — | EP | disclosed |