SCHEMBL17083873

SCHEMBL17083873

CCCCCC[C@H](CCCCCCCCCCC(=O)Oc1ccc(N=C=O)cc1)OC(=O)CCC(=O)Oc1ccc(OC#N)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ MAPT P10636 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ LMNA P02545 3/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ CNR2 P34972 2/20 0.36
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ PRKCA P17252 1/20 0.34
▸ PRKCE Q02156 1/20 0.34
▸ PRKCQ Q04759 1/20 0.34
▸ PRKCD Q05655 1/20 0.34
▸ CA2 P00918 2/20 0.34
▸ HTR1A P08908 1/20 0.34
▸ HTR1B P28222 1/20 0.34
▸ ENPP2 Q13822 1/20 0.33
▸ LPAR2 Q9HBW0 1/20 0.33
▸ LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17086056 0.93 KMT2A (0.44) KMT2ASMN1; SMN2MAPTMAPK1LMNA
SCHEMBL17083878 0.93 KMT2A (0.37) KMT2ASMN1; SMN2MAPTMAPK1LMNA
SCHEMBL17083849 0.92 KMT2A (0.39) KMT2ASMN1; SMN2NPC1RAB9ACA2
SCHEMBL17083869 0.91 PRKCA (0.39) KMT2ASMN1; SMN2MAPTALDH1A1CNR2
SCHEMBL17083819 0.89 ALDH1A1 (0.38) MAPTMAPK1LMNAALDH1A1CNR2
SCHEMBL17083813 0.87 TLR2 (0.41) LMNAALDH1A1CNR2PRKCAPRKCE
SCHEMBL17083832 0.87 TLR2 (0.40) LMNAALDH1A1CNR2PRKCAPRKCE
SCHEMBL17083871 0.86 KMT2A (0.39) KMT2ASMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL17083861 0.86 KMT2A (0.38) KMT2ASMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL17086055 0.85 KMT2A (0.41) KMT2ASMN1; SMN2MAPTMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328192-B2 Bio-based monomers and polymers BEZWADA BIOMEDICAL, LLC (US) 2016-05-03 — — US disclosed
US-20150259464-A1 BIO-BASED MONOMERS AND POLYMERS BEZWADA BIOMEDICAL, LLC 2015-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259464-A1 BIO-BASED MONOMERS AND POLYMERS FHIT, MGAM, BPGM KMT2A 4052/4885SMN1; SMN2 4223/4885MAPT 2608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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