Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794451 | 0.99 | INSR (0.32) | INSRIGF1RGAAALOX15MAPK1 | |
| SCHEMBL1708363 | 0.89 | INSR (0.34) | INSRIGF1RGAAALOX15 | |
| SCHEMBL1708122 | 0.88 | MAPT (0.33) | INSRIGF1R | |
| SCHEMBL1707879 | 0.87 | MAPT (0.34) | INSRIGF1R | |
| SCHEMBL1708264 | 0.86 | ALDH1A1 (0.34) | INSRIGF1RGAA | |
| SCHEMBL1708105 | 0.86 | NTRK1 (0.38) | INSRIGF1RGAAMAPK1 | |
| SCHEMBL10011727 | 0.86 | FFAR1 (0.41) | — | |
| SCHEMBL1708250 | 0.86 | ALDH1A1 (0.34) | INSRIGF1RGAA | |
| SCHEMBL1708241 | 0.85 | NTRK1 (0.38) | INSRIGF1RGAAMAPK1 | |
| SCHEMBL1708390 | 0.84 | FFAR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |