SCHEMBL17084321

SCHEMBL17084321

CCCC1(CCC)c2cc(/C(C)=N/OC(C)=O)ccc2-c2ccc([N+](=O)[O-])cc21

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.36
▸ POLB P06746 2/20 0.36
▸ HTT P42858 2/20 0.36
▸ GAA P10253 2/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ KMT2A Q03164 4/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ XDH P47989 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ ESPL1 Q14674 1/20 0.34
▸ CA12 O43570 1/20 0.34
▸ CA9 Q16790 1/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18122989 1.00 MAPT (0.36) MAPTPOLBHTTGAAMAPK1
SCHEMBL18848196 0.95 MAPT (0.35) MAPTPOLBHTTGAAMAPK1
SCHEMBL16556665 0.94 ESPL1 (0.38) MAPTPOLBHTTGAAMAPK1
SCHEMBL29365660 0.94 ESPL1 (0.38) MAPTPOLBHTTGAAMAPK1
SCHEMBL17084325 0.93 MAPT (0.41) MAPTPOLBHTTGAAMAPK1
SCHEMBL17056190 0.89 CRHBP (0.34) MAPTPOLBHTTGAAMAPK1
SCHEMBL17056225 0.87 KMT2A (0.38) MAPTPOLBHTTKMT2AALDH1A1
SCHEMBL17084361 0.85 ESPL1 (0.38) MAPTPOLBHTTGAAMAPK1
SCHEMBL16556668 0.85 MAPT (0.40) MAPTHTTKMT2AKDM4EALDH1A1
SCHEMBL17084320 0.85 HTT (0.39) MAPTPOLBHTTGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 — — US disclosed
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 — — US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 — — US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR AFF1, AFF2, FTO MAPT 2875/4885POLB 1267/4885HTT 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback