SCHEMBL16556668

SCHEMBL16556668

CCCCC(=O)O/N=C(\C)c1ccc2c(c1)C(CCCC)(CCCC)c1cc([N+](=O)[O-])ccc1-2

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.40
▸ KMT2A Q03164 6/20 0.40
▸ ALDH1A1 P00352 5/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ ESPL1 Q14674 1/20 0.38
▸ HDAC3 O15379 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ HDAC2 Q92769 1/20 0.36
▸ MEN1 O00255 3/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ LMNA P02545 3/20 0.35
▸ HTT P42858 2/20 0.35
▸ CNR1 P21554 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ GPR55 Q9Y2T6 1/20 0.35
▸ BCL9 O00512 1/20 0.34
▸ CTNNB1 P35222 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365660 0.91 ESPL1 (0.38) MAPTKMT2AALDH1A1TDP1ESPL1
SCHEMBL16556665 0.91 ESPL1 (0.38) MAPTKMT2AALDH1A1TDP1ESPL1
SCHEMBL16556670 0.87 XDH (0.43) MAPTKMT2AALDH1A1TDP1MEN1
SCHEMBL16550621 0.87 XDH (0.43) MAPTKMT2AALDH1A1TDP1MEN1
SCHEMBL17084321 0.85 MAPT (0.36) MAPTKMT2AALDH1A1TDP1ESPL1
SCHEMBL18122989 0.85 MAPT (0.36) MAPTKMT2AALDH1A1TDP1ESPL1
SCHEMBL16550544 0.84 ESPL1 (0.41) MAPTKMT2AALDH1A1TDP1ESPL1
SCHEMBL16550542 0.84 ESPL1 (0.41) MAPTKMT2AALDH1A1TDP1ESPL1
SCHEMBL16550663 0.82 MAPK1 (0.47) MAPTKMT2AALDH1A1ESPL1HDAC3
SCHEMBL18012803 0.81 ESPL1 (0.36) MAPTKMT2AALDH1A1TDP1ESPL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9316906-B2 Fluorene oxime ester compound, photopolymerization initiator and photoresist composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-04-19 — — US disclosed
US-9316906-B2 Fluorene oxime ester compound, photopolymerization initiator and photoresist composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-04-19 — — US disclosed
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2015-04-23 — — US disclosed
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2015-04-23 — — US disclosed
EP-2845845-A1 NOVEL OXIMESTER FLUORINE COMPOUND, AND PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION COMPRISING SAME Korea Research Institute of Chemical Technology (KR) 2015-03-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME PPOX, FTO, PAM MAPT 585/4885KMT2A 453/4885ALDH1A1 2606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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