Sugi Predict

Sugi Predict / Compounds / SCHEMBL17084328

SCHEMBL17084328

SCHEMBL17084328

CCCC1(CCC)c2cc(C(=O)/C(C)=N/OC(C)=O)ccc2-c2ccc(C(=O)c3ccc([N+](=O)[O-])cc3)cc21

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ GAA P10253 2/20 0.38
▸ LMNA P02545 1/20 0.38
▸ POLB P06746 3/20 0.36
▸ SRD5A2 P31213 2/20 0.36
▸ HTT P42858 1/20 0.36
▸ MAPK1 P28482 3/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ CES1 P23141 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17084325 0.90 MAPT (0.41) MAPTALDH1A1TDP1GAALMNA
SCHEMBL17084332 0.87 MAPT (0.38) MAPTALDH1A1TDP1GAALMNA
SCHEMBL17084364 0.83 MAPK1 (0.49) MAPTALDH1A1TDP1GAALMNA
SCHEMBL17084321 0.83 MAPT (0.36) MAPTALDH1A1TDP1GAAPOLB
SCHEMBL18122989 0.83 MAPT (0.36) MAPTALDH1A1TDP1GAAPOLB
SCHEMBL17084365 0.83 MAPT (0.40) MAPTALDH1A1TDP1GAALMNA
SCHEMBL17084363 0.82 MAPT (0.44) MAPTALDH1A1TDP1GAALMNA
SCHEMBL18122995 0.81 APEX1 (0.38) MAPTPOLBL3MBTL1KMT2A
SCHEMBL17084367 0.81 ALDH1A1 (0.43) MAPTALDH1A1TDP1GAALMNA
SCHEMBL17084341 0.80 MAPT (0.33) MAPTALDH1A1TDP1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 — — US disclosed
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 — — US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 — — US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR AFF1, AFF2, FTO MAPT 2875/4885ALDH1A1 290/4885TDP1 2676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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