SCHEMBL17084341

SCHEMBL17084341

CCCC1(CCC)c2cc(C(=O)/C(CCCl)=N/OC(C)=O)ccc2-c2ccc([N+](=O)[O-])cc21

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.33
▸ KMT2A Q03164 5/20 0.33
▸ MEN1 O00255 4/20 0.33
▸ HTT P42858 3/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ POLB P06746 3/20 0.32
▸ ALDH1A1 P00352 7/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ MAPK1 P28482 2/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ AKR1B1 P15121 1/20 0.32
▸ BCL9 O00512 1/20 0.31
▸ CTNNB1 P35222 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ LMNA P02545 2/20 0.31
▸ ESPL1 Q14674 1/20 0.30
▸ NPC1 O15118 1/20 0.30
▸ RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17056193 0.88 CYP1A2 (0.33) MAPTKMT2AMEN1HTTRXFP1
SCHEMBL17084339 0.86 ALDH1A1 (0.42) MAPTKMT2AMEN1HTTPOLB
SCHEMBL17084331 0.85 MAPT (0.34) MAPTKMT2AHTTPOLBALDH1A1
SCHEMBL18122989 0.85 MAPT (0.36) MAPTKMT2AMEN1HTTPOLB
SCHEMBL17084321 0.85 MAPT (0.36) MAPTKMT2AMEN1HTTPOLB
SCHEMBL18123008 0.84 ALDH1A1 (0.44) MAPTKMT2AMEN1POLBALDH1A1
SCHEMBL20061892 0.84 SMN1; SMN2 (0.41) MAPTKMT2AMEN1HTTALDH1A1
SCHEMBL17056225 0.80 KMT2A (0.38) MAPTKMT2AMEN1HTTPOLB
SCHEMBL17084328 0.80 MAPT (0.40) MAPTKMT2AMEN1HTTPOLB
SCHEMBL18848196 0.80 MAPT (0.35) MAPTKMT2AMEN1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 — — US disclosed
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 — — US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 — — US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR AFF1, AFF2, FTO MAPT 2875/4885KMT2A 314/4885MEN1 1845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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