SCHEMBL1708797

SCHEMBL1708797

Nc1c(OC=O)cc(C(=O)O)c(N)c1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.37
KMT2A Q03164 6/20 0.34
ALDH1A1 P00352 4/20 0.34
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
GFER P55789 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
POLB P06746 2/20 0.31
GAA P10253 2/20 0.31
HPGD P15428 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 4/20 0.31
MEN1 O00255 4/20 0.31
THRB P10828 3/20 0.31
USP2 O75604 2/20 0.31
PKM P14618 2/20 0.31
MCL1 Q07820 2/20 0.31
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18504200 0.79 CA12 (0.38) KDM4EKMT2AALDH1A1LCKFYN
SCHEMBL10001431 0.77 LCK (0.41) KDM4EALDH1A1LCKFYNGAA
SCHEMBL1709593 0.77 KDM4E (0.50) KDM4EKMT2AALDH1A1GFERRXFP1
SCHEMBL14944744 0.74 LCK (0.42) KDM4EALDH1A1LCKFYNPOLB
SCHEMBL1708800 0.71 IDO1 (0.43) KDM4EKMT2AALDH1A1GFERRXFP1
SCHEMBL19829826 0.70 APP (0.41) KDM4EKMT2AALDH1A1POLBGAA
SCHEMBL12349988 0.69 LCK (0.39) KDM4EALDH1A1LCKFYNGAA
SCHEMBL18269486 0.69 ALDH1A1 (0.42) KDM4EKMT2AALDH1A1GFERRXFP1
SCHEMBL16351578 0.68 ALDH1A1 (0.43) KDM4EALDH1A1LCKFYNHPGD
SCHEMBL17878193 0.68 LCK (0.38) KDM4EALDH1A1LCKFYNGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150062519-A1 ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC (JP) 2015-03-05 US disclosed
US-8906474-B2 Alignment film, composition for forming alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2014-12-09 US disclosed
US-20120088040-A1 ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE MAGNOLIA WHITE CORPORATION (JP) 2012-04-12 US disclosed