Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708800 | 0.86 | IDO1 (0.43) | ALDH1A1KDM4EMAPTPTGS2KMT2A | |
| SCHEMBL12535968 | 0.84 | KDM4E (0.40) | ALDH1A1KDM4EMAPTPTPN1PTGS2 | |
| SCHEMBL17774729 | 0.79 | HTT (0.52) | ALDH1A1KDM4EMAPTPTPN1PTGS2 | |
| SCHEMBL2138202 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTPTPN1PTGS2 | |
| SCHEMBL17779267 | 0.75 | PTGDR2 (0.41) | ALDH1A1KDM4EMAPTPTPN1PTGS2 | |
| SCHEMBL14182693 | 0.73 | GRM1 (0.40) | ALDH1A1KDM4EMAPTPTPN1PTGS2 | |
| SCHEMBL17779181 | 0.73 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTPTPN1PTGS2 | |
| SCHEMBL7714364 | 0.73 | KMT2A (0.54) | ALDH1A1KDM4EMAPTPTPN1PTGS2 | |
| SCHEMBL30978804 | 0.73 | KMT2A (0.54) | ALDH1A1KDM4EMAPTPTPN1PTGS2 | |
| SCHEMBL10001431 | 0.73 | LCK (0.41) | ALDH1A1KDM4EMAPTPTPN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | ALDH1A1 3550/4885KDM4E 1350/4885MAPT 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.