SCHEMBL10001431

SCHEMBL10001431

O=COc1cc(C(=O)O)c(C(=O)O)cc1OC=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
HSD17B10 Q99714 3/20 0.37
TSHR P16473 2/20 0.37
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
CYP1A2 P05177 1/20 0.35
CFD P00746 1/20 0.34
MYC P01106 1/20 0.34
UNG P13051 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA7 P43166 1/20 0.33
TPMT P51580 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14944744 0.91 LCK (0.42) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL16351578 0.89 ALDH1A1 (0.43) LCKFYNHSD17B10ALDH1A1KDM4E
SCHEMBL12349988 0.86 LCK (0.39) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL14904503 0.84 TSHR (0.42) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL17878193 0.80 LCK (0.38) LCKFYNHSD17B10TSHRALDH1A1
SCHEMBL12997844 0.80 CFD (0.47) LCKHSD17B10ALDH1A1KDM4ECFD
SCHEMBL16351608 0.77 POLB (0.51) ALDH1A1KDM4E
SCHEMBL12285464 0.77 ALOX5 (0.39) LCKFYNALDH1A1KDM4EHPGD
SCHEMBL16351600 0.77 POLB (0.54) HSD17B10TSHRALDH1A1KDM4ECYP1A2
SCHEMBL12535968 0.77 KDM4E (0.40) HSD17B10TSHRALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265247-A1 PROCESS FOR PREPARING POLYIMIDES TECHNISCHE UNIVERSITÄT WIEN (AT) 2023-08-24 US disclosed
US-11650499-B2 Photosensitive resin composition, organic EL element barrier rib, and organic EL element SHOWA DENKO K.K. (JP) 2023-05-16 US disclosed
US-9975108-B2 Adsorbent for adsorption heat pumps, production method thereof, and adsorption heat pump FUJITSU LIMITED (JP) 2018-05-22 US disclosed
US-20180112039-A1 PROCESS FOR PRODUCING POLYIMIDES TECHNISCHE UNIVERSITÄT WIEN (AT) 2018-04-26 US disclosed
US-9394221-B2 Method for manufacturing benzenetetracarboxylic acid JX NIPPON OIL & ENERGY COMPANY (JP) 2016-07-19 US disclosed
US-20160045892-A1 ADSORBENT FOR ADSORPTION HEAT PUMPS, PRODUCTION METHOD THEREOF, AND ADSORPTION HEAT PUMP FUJITSU LIMITED (JP) 2016-02-18 US disclosed
US-20150056367-A1 COMPOSITION FOR FORMING LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT SOKI CORPORATION (JP) 2015-02-26 US disclosed
US-20140378645-A1 LIQUID CRYSTAL ALIGNING AGENT WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2014-12-25 US disclosed
US-20140018460-A1 COMPOSITIONS FOR IMPROVING POLYESTERS NEXAM CHEMICAL AB (SE) 2014-01-16 US disclosed
US-20140018569-A1 METHOD FOR MANUFACTURING BENZENETETRACARBOXYLIC ACID JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-01-16 US disclosed
US-20120160393-A1 METHOD FOR MAKING BISTABLE NEMATIC LIQUID-CRYSTAL DEVICES CDC PROPRIETE INTELLECTUELLE (FR) 2012-06-28 US disclosed
US-20110189581-A1 COMPOUND, CROSS-LINKED MATERIAL THEREOF, DOUBLE CROSS-LINKED POLYMER THEREOF, AND ELECTROLYTE MEMBRANE, ELECTRODE FOR FUEL CELL AND FUEL CELL INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-04 US disclosed
US-7690783-B2 Ink for inkjet printing, lithographic printing plate using it and method for making such plate FUJIFILM CORPORATION (JP) 2010-04-06 US disclosed
US-20080057448-A1 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-20080050683-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2008-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378645-A1 LIQUID CRYSTAL ALIGNING AGENT CYP17A1, AUP1, NR5A1 LCK 4339/4885FYN 3954/4885HSD17B10 717/4885
US-20140018569-A1 METHOD FOR MANUFACTURING BENZENETETRACARBOXYLIC ACID HAAO, HAO2, HPD LCK 2743/4885FYN 2525/4885HSD17B10 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.