SCHEMBL1708798

SCHEMBL1708798

Nc1cc(N)cc(CS(=O)(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TSHR P16473 3/20 0.39
HSD17B10 Q99714 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
NT5E P21589 1/20 0.34
CASP1 P29466 3/20 0.33
CYP3A4 P08684 2/20 0.33
RECQL P46063 2/20 0.33
CASP7 P55210 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
CA9 Q16790 3/20 0.33
CYP2D6 P10635 1/20 0.32
LMNA P02545 2/20 0.32
CA12 O43570 2/20 0.31
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18872934 0.86 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10TDP1NT5E
SCHEMBL24407435 0.82 SLC22A12 (0.31) ALDH1A1TSHRHSD17B10TDP1CA1
SCHEMBL6401924 0.80 ALDH1A1 (0.53) ALDH1A1TSHRHSD17B10TDP1CASP1
SCHEMBL30010246 0.80 ALDH1A1 (0.53) ALDH1A1TSHRHSD17B10TDP1CASP1
SCHEMBL9464992 0.80 ALDH1A1 (0.44) ALDH1A1TSHRNT5ECYP3A4CA1
SCHEMBL1335821 0.76 TSHR (0.50) ALDH1A1TSHRTDP1NT5ECYP3A4
SCHEMBL19306408 0.76 PGK1 (0.40) ALDH1A1TSHRCA1CA2MAOA
SCHEMBL15665068 0.76 ALDH1A1 (0.35) ALDH1A1TSHRHSD17B10TDP1NT5E
SCHEMBL28629801 0.74 PGK1 (0.39) ALDH1A1CA1CA2MAOAMAOB
SCHEMBL15665442 0.73 MAOA (0.34) ALDH1A1TSHRHSD17B10TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150062519-A1 ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC (JP) 2015-03-05 US disclosed
US-8906474-B2 Alignment film, composition for forming alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2014-12-09 US disclosed
US-20120088040-A1 ALIGNMENT FILM, COMPOSITION FOR FORMING ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE MAGNOLIA WHITE CORPORATION (JP) 2012-04-12 US disclosed