Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 6/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565755 | 0.90 | ALDH1A1 (0.50) | CRHR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL17089949 | 0.90 | ALDH1A1 (0.50) | CRHR1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL17090355 | 0.86 | CRHR1 (0.42) | CRHR1FYNALDH1A1LMNAOPRK1 | |
| SCHEMBL13565190 | 0.86 | CRHR1 (0.42) | CRHR1FYNALDH1A1LMNAOPRK1 | |
| SCHEMBL11934886 | 0.85 | CRHR1 (0.46) | CRHR1CYP3A4 | |
| SCHEMBL13438760 | 0.85 | CRHR1 (0.46) | CRHR1CYP3A4 | |
| SCHEMBL13564748 | 0.85 | BRD4 (0.38) | CRHR1ALDH1A1 | |
| SCHEMBL17090297 | 0.85 | BRD4 (0.38) | CRHR1ALDH1A1 | |
| SCHEMBL11935134 | 0.85 | CRHR1 (0.44) | CRHR1FYNALDH1A1LMNAOPRM1 | |
| SCHEMBL17090251 | 0.85 | CRHR1 (0.44) | CRHR1FYNALDH1A1LMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |